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E45309

Sigma-Aldrich

Ethyl phenylpropiolate

98%

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About This Item

Linear Formula:
C6H5C≡CCOOC2H5
CAS Number:
2216-94-6
Molecular Weight:
174.20
Beilstein:
639637
EC Number:
218-703-8
MDL number:
MFCD00009185
UNSPSC Code:
12352100
PubChem Substance ID:
24894561
NACRES:
NA.22

Assay

98%

form

liquid

refractive index

n20/D 1.552 (lit.)

bp

260-270 °C (lit.)

density

1.055 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CCOC(=O)C#Cc1ccccc1

InChI

1S/C11H10O2/c1-2-13-11(12)9-8-10-6-4-3-5-7-10/h3-7H,2H2,1H3

InChI key

ACJOYTKWHPEIHW-UHFFFAOYSA-N

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SDBB1902
STBK5840
STBJ2546
STBH2949
S16570V

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C S Baxter et al.
Carcinogenesis, 10(10), 1855-1861 (1989-10-01)
Responses of various cells of the epidermis and dermis to topically applied agents have been implicated in the mechanism of multistage mouse tumorigenesis. These responses have been discussed almost entirely in the context of a single promoter treatment, although tumor
S K Gilmour et al.
Carcinogenesis, 13(1), 51-56 (1992-01-01)
Single applications of 12-O-tetradecanoylphorbol-13-acetate (TPA), mezerein or ethyl phenylpropriolate (EPP) to mouse skin at appropriate doses cause similar degrees of hyperplasia and comparable levels of induction of epidermal ornithine decarboxylase (ODC) activity. Multiple (n = 5) treatments with these agents
E Patrick et al.
Toxicology and applied pharmacology, 81(3 Pt 1), 476-490 (1985-12-01)
The possibility that chemicals induce skin irritation by multiple mechanisms was studied in laboratory mice. The time course and dose response to topical application of phenol, croton oil, benzalkonium chloride, ethyl phenylpropiolate (EPP), and methyl salicylate were compared. The responses
E Patrick et al.
The Journal of investigative dermatology, 88(3 Suppl), 24s-31s (1987-03-01)
The time course, dose response, components of inflammation, and involvement of putative mediators of inflammation in irritation induced by different chemicals was compared using a mouse ear swelling technique. Differences in time courses of inflammation produced by the irritants were
C E Weeks et al.
Proceedings of the National Academy of Sciences of the United States of America, 79(19), 6028-6032 (1982-10-01)
The role of ornithine decarboxylase (OrnDCase, EC 4.1.1.17) and of the polyamines [putrescine (Put), spermidine (Spd), and spermine (Spm)] in mouse skin tumor promotion was investigated by the use of alpha-difluoromethylornithine (CHF2-Orn), an enzyme-activated irreversible inhibitor of OrnDCase. 12-O-Tetradecanoylphorbol 13-acetate
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