T8566

L-Tyrosine

99.0-101.0%, suitable for cell culture, BioXtra, non-animal source

• Synonym(s): (S)-2-Amino-3-(4-hydroxyphenyl)propionic acid, 3-(4-Hydroxyphenyl)-L-alanine
• Linear Formula: 4-(HO)C₆H₄CH₂CH(NH₂)CO₂H
• CAS Number: 60-18-4
• Molecular Weight: 181.19
• Beilstein: 392441
• EC Number: 200-460-4
• MDL number: MFCD00002606
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24900543
• NACRES: NA.26

Properties

• Product Name: L-Tyrosine, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 99.0-101.0%
• biological source: non-animal source
• Agency: USP/NF; meets EP testing specifications; meets USP testing specifications
• product line: BioXtra
• Assay: 99.0-101.0%
• form: powder
• optical activity: [α]25/D 11.2 to 9.8°, c = 5 in 1 M HCl (Specific Rotation 6.1 - 7.8 °)
• shelf life: limited shelf life, expiry date on the label
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, tested
• color: white to off-white
• mp: >300 °C (dec.) (lit.)
• solubility: 1 M HCl: 25 mg/mL
• cation traces: Fe: ≤10 ppm; NH₄⁺: ≤0.02%
• application(s): pharmaceutical (small molecule)
• functional group: (phenol)
• storage temp.: room temp
• SMILES string: N[C@@H](Cc1ccc(O)cc1)C(O)=O
• InChI: 1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1
• InChI key: OUYCCCASQSFEME-QMMMGPOBSA-N

Description

General description

L-Tyrosine, an essential amino acid, plays a vital role in biochemical and cell culture research. In biochemical studies, L-Tyrosine is significant as a precursor to neurotransmitters like dopamine, norepinephrine, and epinephrine, which influence cellular communication and play a role in mood, attention, and energy levels. It also contributes to the synthesis of thyroid hormones, regulating metabolic processes. L-Tyrosine is employed to support cell growth and protein synthesis, facilitating experiments on cell maintenance and repair, making it a valuable tool in biochemical and cell culture investigations.

Application

L-Tyrosine has been used as a supplement in Dulbecco′s modified Eagle′s medium for culturing SY5Y neuroblastoma cells for stable isotope labeling of amino acids on cell culture (SILAC).[1]

Biochem/physiol Actions

L-Tyrosine consists of a polar side chain and is a non-essential amino acid. It is utilized by cells to synthesize proteins that are involved in signal transduction. L-Tyrosine acts as a receiver of phosphate groups that are transferred by kinases.[2][3]

Features and Benefits

• Suitable for Cell Culture and Biochemical research
• High-quality compound suitable for multiple research applications

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Amino acid precursor of dopamine and other catecholamines

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Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves