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RAB0126

Sigma-Aldrich

Human BLC / BCA-1 / CXCL13 ELISA Kit

for serum, plasma, cell culture supernatant and urine

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type urine
sample type plasma
sample type cell culture supernatant(s)
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1.5 pg/mL
standard curve range: 1.37-1000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... CXCL13(10563)

General description

The CXCL13 (C-X-C motif chemokine ligand 13 ) gene codes for a CXC subtype of the chemokine superfamily and it is also known as B cell-attracting chemokine 1. The CXCL13 gene is mapped to human chromosome 4q21.1.

Immunogen

Recombinant Human BLC

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

CXCL13 (C-X-C motif chemokine ligand 13 ) contributes to the process of tumorigenesis in breast cancer, neuronal cancer and prostatic cancer. CXCL13 serves as an important marker for Lyme neuroborreliosis. CXCL13 mediates B-cell migration,survival, and maturation. CXCL13 is a ligand for CXCR5 and possesses immune function such as antibody production.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit Components Also Available Separately

Product No.
Description
SDS
  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)SDS
  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

Pictograms

Corrosion
GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Damien Hermand et al.
Molecular cell, 26(4), 553-563 (2007-05-29)
DNA replication is initiated by recruitment of Cdc18 to origins. During S phase, CDK-dependent destruction of Cdc18 occurs. We show that when DNA replication stalls, Cdc18 persists in a chromatin-bound complex including the checkpoint kinases Rad3 and Rad26. Rad26 directly
Elevated C?X?C motif ligand 13 and B?cell?activating factor levels in neuromyelitis optica during remission.
Wang S, et al.
Brain and Behavior, 7(4), e00648-e00648 (2017)
Chemokine/chemokine receptor nomenclature.
Bacon K, et al.
Journal of Leukocyte Biology, 70, 465-466 (2001)
Cerebrospinal fluid B-lymphocyte chemoattractant CXCL13 in the diagnosis of acute Lyme neuroborreliosis in children.
Barstad B, et al.
The Pediatric Infectious Disease Journal, 36(12), e286-e292 (2017)
MDC and BLC are independently associated with the significant risk of early stage lung adenocarcinoma.
Zhang Y, et al.
Oncotarget, 7(50), 83051-83051 (2016)
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