R7774

Riboflavin 5′-phosphate sodium salt hydrate

meets USP testing specifications

• Synonym(s): Flavin Mononucleotide
• Empirical Formula (Hill Notation): C₁₇H₂₀N₄NaO₉P · xH₂O
• Molecular Weight: 478.33 (anhydrous basis)
• EC Number: 204-988-6
• MDL number: MFCD00150992
• UNSPSC Code: 12352205
• eCl@ss: 34058005
• PubChem Substance ID: 329823649
• NACRES: NA.21

Properties

• Agency: USP/NF; meets USP testing specifications
• Quality Level: 200
• Assay: 73.0-79.0% dry basis (BASED ON % RIBOFLAVIN)
• form: powder
• application(s): pharmaceutical (small molecule)
• storage temp.: −20°C
• SMILES string: O.[Na+].Cc1cc2N=C3C(=O)NC(=O)N=C3N(C[C@H](O)[C@H](O)[C@H](O)COP(O)([O-])=O)c2cc1C
• InChI: 1S/C17H21N4O9P.Na.H2O/c1-7-3-9-10(4-8(7)2)21(15-13(18-9)16(25)20-17(26)19-15)5-11(22)14(24)12(23)6-30-31(27,28)29;;/h3-4,11-12,14,22-24H,5-6H2,1-2H3,(H,20,25,26)(H2,27,28,29);;1H2/q;+1;/p-1/t11-,12+,14-;;/m0../s1
• InChI key: BHRVCJBIICJWTH-APQIITSESA-M

Description

General description

Riboflavin 5′-phosphate (flavin mononucleotide (FMN)) is a vitamin B₁₂ derivative, containing isoalloxazine ring system.[1]

Application

Riboflavin 5′-phosphate sodium salt hydrate has been used:

• as a photosensitizing agent to assess in vitro efficacy of photodynamic therapy (PDT) on fungi[2]
• to evaluate its in vivo delivery in rat corneas[3]
• as a component in Vitamin and growth factor stock mix[4]

Biochem/physiol Actions

Riboflavin 5′-phosphate (flavin mononucleotide (FMN)) acts as a coenzyme in intermediary metabolism. Phosphorylation of vitamin B₁₂ by flavokinase yields FMN.[1]

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves