71726

Sodium dodecyl sulfate

suitable for ion pair chromatography, LiChropur^™, ≥99.0%

• Synonym(s): Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate
• Linear Formula: CH₃(CH₂)₁₁OSO₃Na
• CAS Number: 151-21-3
• Molecular Weight: 288.38
• Beilstein: 3599286
• EC Number: 205-788-1
• MDL number: MFCD00036175
• UNSPSC Code: 12000000
• eCl@ss: 39093306
• PubChem Substance ID: 329763468
• NACRES: NB.21

Properties

• Quality Level: 100
• description: anionic; 62
• Assay: ≥99.0% (GC); ≥99.0%
• form: rod
• quality: LiChropur^™
• mol wt: 288.38 g/mol
• technique(s): ion pair chromatography: suitable
• mp: 204-207 °C (lit.)
• solubility: water: soluble
• λ: 10 % in H₂O
• UV absorption: λ: 210 nm A_max: 0.1; λ: 220 nm A_max: 0.06; λ: 230 nm A_max: 0.04; λ: 260 nm A_max: 0.02; λ: 500 nm A_max: 0.02
• HLB: 40
• suitability: corresponds to standard for RP gradient test; corresponds to standard for filter test
• SMILES string: [Na+].CCCCCCCCCCCCOS([O-])(=O)=O
• InChI: 1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
• InChI key: DBMJMQXJHONAFJ-UHFFFAOYSA-M

Description

General description

Sodium dodecyl sulfate (SDS) is a detergent suitable to denature proteins. It is a long-chain aliphatic group which has negatively charged sulfate, hence making it amphipathic detergent in nature.[1]

Application

Anionic detergent

SDS may be used:

• in peptide mapping and protein analysis by gel electrophoresis.[2]
• to utilize in designing formulations and its effect on adsorption and micellization parameters.[3]
• in measuring protein-SDS complexes and SDS solution in guanidine hydrochloride using gel chromatography.[4]
• in seperating protein subunits dissociated with SDS using Hydroxylapatite chromatography.[5]

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H228,H302 + H332,H315,H318,H335,H412
• Precautionary Statements: P210 - P273 - P280 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 4.1B - Flammable solid hazardous materials
• WGK: WGK 2
• Flash Point(F): 338.0 °F
• Flash Point(C): 170 °C
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves