LM1902

17:0-20:4 PI(5)P

Avanti Research^™ - A Croda Brand LM1902, powder

• Synonym(s): 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-myo-inositol-5′-phosphate) (ammonium salt)
• Empirical Formula (Hill Notation): C₄₆H₈₈N₂O₁₆P₂
• CAS Number: 1246304-69-7
• Molecular Weight: 987.14
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• form: powder
• manufacturer/tradename: Avanti Research^™ - A Croda Brand LM1902
• packaging: 1 ea of 1 × (with stopper and crimp cap (LM1902-1EA))
• application(s): lipidomics; metabolomics
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](OP(O)([O-])=O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+]
• InChI: 1S/C46H82O16P2.2H3N/c1-3-5-7-9-11-13-15-17-19-20-21-23-25-27-29-31-33-35-40(48)60-38(36-58-39(47)34-32-30-28-26-24-22-18-16-14-12-10-8-6-4-2)37-59-64(56,57)62-46-43(51)41(49)42(50)45(44(46)52)61-63(53,54)55;;/h11,13,17,19,21,23,27,29,38,41-46,49-52H,3-10,
• InChI key: IOJKXWHTFCVKEI-QBMVDDEMSA-N

Description

General description

Phosphatidylinositol 5-Phosphate (PI5P) is present in the endosomes, trans-Golgi network and smooth endoplasmic reticulum. It is abundantly localized to the plasma membrane but also found in the intracellular membranes of the organelles.

Biochem/physiol Actions

Phosphorylation of phosphatidylinositol 5-phosphate (PI5P) by phosphatidylinositol 5-phosphate (PI5P) type II PIPKs (PIPKIIs) produces phosphatidylinositol 4,5-bisphosphate (PI-4,5-P2), which, is a potent signaling molecule. PI5P is a lipid messenger associated with stress-induced pathways in the nucleus. It is known to possess housekeeping functions and aids in cell activation during bacterial infections.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (LM1902-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids