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SMB00083

Sigma-Aldrich

Sweroside

≥95% (LC/MS-ELSD)

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About This Item

Empirical Formula (Hill Notation):
C16H22O9
CAS Number:
14215-86-2
Molecular Weight:
358.34
MDL number:
MFCD09954487
UNSPSC Code:
12352205
PubChem Substance ID:
329824761
NACRES:
NA.25

Assay

≥95% (LC/MS-ELSD)

form

solid

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

SMILES string

OC[C@H]1O[C@@H](O[C@@H]2OC=C3[C@@H](CCOC3=O)[C@H]2C=C)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C16H22O9/c1-2-7-8-3-4-22-14(21)9(8)6-23-15(7)25-16-13(20)12(19)11(18)10(5-17)24-16/h2,6-8,10-13,15-20H,1,3-5H2/t7-,8+,10-,11-,12+,13-,15+,16+/m1/s1

InChI key

VSJGJMKGNMDJCI-ZASXJUAOSA-N

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General description

Natural product derived from plant source.
Sweroside is an active component of iridoid glycoside, with a molecular weight of 358.344 Da. It is found in variety of plant species.

Application

Sweroside has been used as a standard in MC-high performance liquid chromatography (HPLC)-ultraviolet (UV) experiment.

Biochem/physiol Actions

Sweroside possesses hepatoprotective, antitumor, antibacterial and antifungal properties. It can be used as a potential therapeutic to treat osteoporosis.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Iridoids and Flavonoids of Four Siberian Gentians: Chemical Profile and Gastric Stimulatory Effect
Olennikov D N, et al.
Molecules (Basel), 20(10), 19172-19188 (2015)
Hui Sun et al.
Fitoterapia, 84, 174-179 (2012-12-04)
Herbal Fructus Corni is a folk medicine with a long history of safe use for treating osteoporosis in postmenopausal women or elderly men in Asia. Sweroside is a bioactive herbal ingredient isolated from Fructus Corni, which has been widely used
Nilgün Oztürk et al.
Planta medica, 72(4), 289-294 (2006-03-25)
Wound healing properties of Gentian (Gentiana lutea ssp. symphyandra) extract and its main constituents, gentiopicroside, sweroside and swertiamarine (compounds 1-3, respectively) were evaluated by comparison with dexpanthenol on cultured chicken embryonic fibroblasts. The extract was also analyzed by HPLC to
Nilgün Oztürk et al.
Phytotherapy research : PTR, 16(7), 627-631 (2002-11-01)
A methanolic extact of Gentiana lutea ssp. symphyandra roots has been investigated for its possible effects on the central nervous system of mice. At doses of 250 and 500 mg/kg (i.p.), the methanol extract of Gentiana roots caused a significant
M M Horn et al.
Phytochemistry, 57(1), 51-56 (2001-05-05)
From the rootstock of Scabiosa columbria L. loganin and sweroside were isolated. Sweroside showed moderate antibacterial activity. Pure sweroside was converted to the sweroside aglycone 1-acetoxy derivative (DABCO/Ac2O) after hydrolysis of the glucose unit. X-ray crystallography of the monoacetate showed
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