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F0537

Sigma-Aldrich

Fusicoccin from Fusicoccum amygdali

≥85% (HPLC)

Synonym(s):

Fusicoccin A

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About This Item

Empirical Formula (Hill Notation):
C36H56O12
CAS Number:
20108-30-9
Molecular Weight:
680.82
MDL number:
MFCD00070322
UNSPSC Code:
12352201
PubChem Substance ID:
24894726
NACRES:
NA.25

biological source

plant (Fusicoccum amygdali)

Quality Level

200

Assay

≥85% (HPLC)

form

solid

storage temp.

−20°C

SMILES string

COCC1CCC2C(C)C(O)C(OC3OC(COC(C)(C)C=C)C(O)C(OC(C)=O)C3O)C4=C(CC(O)C4(C)C=C12)C(C)COC(C)=O

InChI

1S/C36H56O12/c1-10-35(6,7)45-17-26-30(41)33(46-21(5)38)31(42)34(47-26)48-32-28-24(18(2)15-44-20(4)37)13-27(39)36(28,8)14-25-22(16-43-9)11-12-23(25)19(3)29(32)40/h10,14,18-19,22-23,26-27,29-34,39-42H,1,11-13,15-17H2,2-9H3/b25-14-

InChI key

KXTYBXCEQOANSX-QFEZKATASA-N

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Application

Fusicoccin (Fusicoccin A), a diterpene glucoside phytotoxin, is used to study 14-3-3-dependent processes such as the activation of H+-ATPase in plants and other client proteins with mode III binding motifs. Fusicoccin is an inducer of a catalase inhibitor that leads to oxidative damage in plants.

Other Notes

A diterpene glucoside with numerous physiological effects on plants.
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A H de Boer
Biochemical Society transactions, 30(4), 416-421 (2002-08-28)
Turgor pressure is a cellular parameter, important for a range of physiological processes in plants, like cell elongation, gas exchange and gravitropic/phototropic bending. Regulation of turgor pressure involves ion and water transport at the expense of metabolic energy (ATP). The
Identification and structure of small-molecule stabilizers of 14-3-3 protein-protein interactions.
Rolf Rose et al.
Angewandte Chemie (International ed. in English), 49(24), 4129-4132 (2010-05-04)
Anja Richter et al.
The Journal of organic chemistry, 76(16), 6694-6702 (2011-07-16)
A synthesis of the fully protected C-ring fragment of the tricyclic diterpene fusicoccin A is reported. The desired cyclopentenyl halides 5a,b are obtained in a total of nine steps. Key transformations of the synthesis sequence are a nonconventional Cr-catalyzed allylic
Renata Kurtyka et al.
Archives of environmental contamination and toxicology, 61(4), 568-577 (2011-03-23)
The effects of cadmium (Cd; 0.1-1000 μM) and fusicoccin (FC) on growth, Cd(2+) content, and membrane potential (E(m)) in maize coleoptile segments were studied. In addition, the E(m) changes and accumulation of Cd and calcium (Ca) in coleoptile segments treated
Tomonobu Toyomasu
Bioscience, biotechnology, and biochemistry, 72(5), 1168-1175 (2008-05-08)
Cyclic diterpenoids are commonly biosynthesized from geranylgeranyl diphosphate (GGDP) through the formation of carbon skeletons by specific cyclases and subsequent chemical modifications, such as oxidation, reduction, methylation, and glucosidation. A variety of diterpenoids are produced in higher plants and fungi.
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