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32593

Supelco

Cambendazole

VETRANAL®, analytical standard

Synonym(s):

Isopropyl 2-(4-thiazolyl)-5-benzimidazolecarbamate

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About This Item

Empirical Formula (Hill Notation):
C14H14N4O2S
CAS Number:
26097-80-3
Molecular Weight:
302.35
Beilstein:
563292
EC Number:
247-459-5
MDL number:
MFCD00864552
UNSPSC Code:
41116107
PubChem Substance ID:
329754047
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CC(C)OC(=O)Nc1ccc2[nH]c(nc2c1)-c3cscn3

InChI

1S/C14H14N4O2S/c1-8(2)20-14(19)16-9-3-4-10-11(5-9)18-13(17-10)12-6-21-7-15-12/h3-8H,1-2H3,(H,16,19)(H,17,18)

InChI key

QZWHWHNCPFEXLL-UHFFFAOYSA-N

General description

Cambendazole is classified under the family of benzimidazole anthelmintic compounds.

Application

Cambendazole may be used as an analytical reference standard for the determination of the analyte in:
  • Bovine muscle samples by ultra-high performance liquid chromatography (UHPLC) coupled to tandem mass spectrometry (MS/MS) operating in ESI mode.
  • Bovine milk samples by LC-ESI-MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Product No.
Description
Pricing

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H361fd

Hazard Classifications

Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK1453
BCCF0930
BCBZ9917
BCBW6201
BCBS4988V

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[Evaluation of the therapeutic activity of albendazole in rats experimentally infected with Strongyloides venezuelensis].
V Amato Neto et al.
Revista do Instituto de Medicina Tropical de Sao Paulo, 28(3), 181-184 (1986-05-01)
[Trial of the modification of immunopathological changes in the muscular phase of trichinosis I. The effect of cambendazole].
K Karmańska et al.
Wiadomosci parazytologiczne, 33(4-5), 517-524 (1987-01-01)
Morphological changes in Capillaria obsignata (Nematoda: Trichuridae) eggs after treatment with cambendazole.
P Dorny et al.
Parasitology research, 74(2), 196-197 (1987-01-01)
R N Beech et al.
Genetics, 138(1), 103-110 (1994-09-01)
Benzimidazole anthelmintics are the most common chemotherapeutic agents used to remove intestinal helminths from farm animals. The development of drug resistance within helminth populations is wide-spread and can render these drugs essentially useless. The mechanism of benzimidazole resistance appears to
Determination of benzimidazoles and levamisole residues in milk by liquid chromatography-mass spectrometry: screening method development and validation.
Jedziniak P, et al.
Journal of Chromatography A, 1216(46), 8165-8172 (2009)
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