8.22339
Phosphoryl chloride
for synthesis
Synonym(s):
Phosphoryl chloride, Phosphorus oxide trichloride, Phosphorus oxychloride
About This Item
vapor pressure
36 hPa ( 20 °C)
Quality Level
Assay
≥99.0% (argenometric)
form
liquid
potency
36 mg/kg LD50, oral (Rat)
pH
1.0 (25 °C, 5 g/L in H2O)
bp
105.3 °C/1013 hPa
mp
1-2 °C
density
1.68 g/cm3 at 20 °C (DIN 51757)
storage temp.
2-30°C
InChI
1S/Cl3OP/c1-5(2,3)4
InChI key
XHXFXVLFKHQFAL-UHFFFAOYSA-N
General description
Application
- A phosphorylating agent for the selective phosphorylation of alcohols, amines, and thiols.
- A dehydrating agent for alcohols, amides, and cyanohydrins.
- A reagent to synthesize Vilsmeier reagent for Vilsmeier-Haack formylation reactions.
- A chlorinating agent for the chlorination of heterocyclic compounds.
- A reagent to prepare dihydroisoquinolines and isoquinolines by cyclization of N-β-phenylethyl amides via Bischler-Napieralski reaction.
Analysis Note
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1 - STOT RE 1 Inhalation
Target Organs
Respiratory Tract
Supplementary Hazards
Storage Class Code
6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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