545716

3-Bromobenzenesulfonyl chloride

96%

• Linear Formula: BrC₆H₄SO₂Cl
• CAS Number: 2905-24-0
• Molecular Weight: 255.52
• MDL number: MFCD00052313
• UNSPSC Code: 12352100
• PubChem Substance ID: 24878844
• NACRES: NA.22

Properties

• Assay: 96%
• refractive index: n20/D 1.593 (lit.)
• bp: 90-91 °C/0.5 mmHg (lit.)
• mp: 30-33 °C
• density: 1.773 g/mL at 25 °C (lit.)
• SMILES string: ClS(=O)(=O)c1cccc(Br)c1
• InChI: 1S/C6H4BrClO2S/c7-5-2-1-3-6(4-5)11(8,9)10/h1-4H
• InChI key: PJGOLCXVWIYXRQ-UHFFFAOYSA-N

Description

General description

3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.

Application

3-Bromobenzenesulfonyl chloride may be used in the preparation of:

• 2-(3-bromophenyl)-5-n-butylfuran
• 2-(3-bromophenyl)-3,6-dimethyl-4,5,6,7-tetrahydrobenzofuran
• 3-bromo-4-(3-bromophenyl)thiophene
• 2,5-bis(3-bromophenyl)-1-methylpyrrole

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves