SAB1305554

MONOCLONAL ANTI-BETA-ACTIN antibody produced in mouse

clone 137CT26.1.1, IgG fraction of antiserum, buffered aqueous solution

• Synonym(s): ACTB, Actin, cytoplasmic 1, Actin, cytoplasmic 1, N-terminally processed, Beta-actin
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100
• antibody form: IgG fraction of antiserum
• antibody product type: primary antibodies
• clone: 137CT26.1.1, monoclonal
• form: buffered aqueous solution
• mol wt: 41737 Da
• species reactivity: mouse, human
• technique(s): immunofluorescence: 1:10-1:50; immunohistochemistry: 1:25; western blot: 1:1000
• isotype: IgG1κ
• NCBI accession no.: NP_001092.1
• UniProt accession no.: P60709
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... ACTB(60)

Description

General description

β-actin (ACTB), a member of the actin multigene family, is an isoform of actin-associated with non-muscle cells. ACTB is a housekeeping gene mapped to human chromosome 7p22.1.

Application

Monoclonal Anti-Beta-Actin antibody produced in mouse has been used in western blotting at a dilution of 1:1000.

Biochem/physiol Actions

β-actin (ACTB) forms the core of the cell cytoskeleton. The polymerization of β-actin is essential for cell physiology. It may serve as a potential chemotherapeutic agent. Mutation in the ACTB gene is implicated in sensory hearing loss, delayed-onset generalized dystonia and a combination of ventral midline malformations. A loss-of-function mutation in the ACTB gene may cause intellectual disability.

Physical form

Supplied in PBS with 0.09% (W/V) sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable