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Key Documents

L5137

Sigma-Aldrich

β-Lactoglobulin A from bovine milk

Isoelectric focusing marker, pI 5.1

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.61

biological source

bovine milk

Quality Level

form

powder

technique(s)

isoelectric focusing (IEF): suitable

pI 

5.1

UniProt accession no.

storage temp.

−20°C

Gene Information

bovine ... LGB(280838)

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General description

Milk from dairy cows contains the protein β-lactoglobulin (BLG). It naturally occurs in a number of genetic variants, and the most prevalent bovine variants are BLG A and BLG B.

Application

β-Lactoglobulin was used in the identification of the genetic variants of κ-casein in milk by isoelectric focusing.

Biochem/physiol Actions

A member of the lipocalin family, βLg is a small protein of 162 amino acids with a molecular mass of ∼18,400 Da. It has an eight-stranded β-barrel (strands A-H) succeeded by a three-turn α-helix and a final β-strand (strand I) that forms part of the dimerization interface.

Certificates of Analysis (COA)

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Identification of the genetic variants of κ-casein in milk by isoelectric focusing electrophoresis.
L H Molina, M Casanova, L A Gonzalez, M Pinto, E Carrasco and C Brito
International Journal of Dairy Technology, 56, 211-214 (2003)
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