Skip to Content
Merck
All Photos(1)

Key Documents

Y0000482

Dihydrotachysterol for system suitability

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Dihydrotachysterol, 9,10-Secoergosta-5,7,22-trien-3β-ol, DHT2

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C28H46O
CAS Number:
Molecular Weight:
398.66
UNSPSC Code:
41116107
NACRES:
NA.24

biological source

synthetic

grade

pharmaceutical primary standard

Agency

EP

API family

dihydrotachysterol

form

solid

manufacturer/tradename

EDQM

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp

113-127 °C

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

SMILES string

C[C@@H]([C@@]1([H])CC[C@@]2([H])/C(CCC[C@@]21C)=C/C=C3[C@@H](C)CC[C@H](O)C/3)/C=C/[C@H](C)C(C)C

InChI

1S/C28H46O/c1-19(2)20(3)12-13-22(5)25-16-17-26-23(10-8-18-28(25,26)6)14-15-24-21(4)9-7-11-27(24)29/h12-15,19-22,25-27,29H,7-11,16-18H2,1-6H3/b13-12+,23-14+,24-15+/t20-,21-,22+,25?,26?,27-,28+/m0/s1

InChI key

DTSXXSAWQHPLEF-GFVAUXBKSA-N

Looking for similar products? Visit Product Comparison Guide

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. Dihydrotachysterol (DHT) is a biologically active synthetic analog of vitamin D. It aids in promoting active calcium and phosphate intestinal absorption. It is also beneficial in the treatment of hypoparathyroidism.

Application

Dihydrotachysterol for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 4

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A L Voigts et al.
Archives of internal medicine, 143(5), 960-963 (1983-05-01)
The available data with regard to the use of calciferol, dihydrotachysterol, and calcifediol in the management of renal insufficiency are reviewed. Very limited data are available with regard to calciferol therapy; with the advent of more active metabolites, the use
I Quack et al.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 113(7), 376-380 (2005-07-19)
The half synthetic Vitamin D analogue dihydrotachysterol (DHT) is widely used for hypocalcaemic hypoparathyroidism following surgical removal of parathyroids. Such treatment generally initiated by surgeons right after surgery has to be continued in clinical practice. Unfortunately, the required careful monitoring
In vivo metabolism of the vitamin D analog, dihydrotachysterol. Evidence for formation of 1 alpha, 25-and 1 beta, 25-dihydroxy-dihydrotachysterol metabolites and studies of their biological activity.
Qaw F, et al.
Test, 268(1), 282-292 (1993)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service