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BCR266

7H-Dibenzo[c,g]carbazole

BCR®, certified reference material

Synonym(s):

3,4,5,6-Dibenzocarbazole

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About This Item

Empirical Formula (Hill Notation):
C20H13N
CAS Number:
Molecular Weight:
267.32
Beilstein:
213015
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

Agency

BCR®

manufacturer/tradename

JRC

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

format

neat

storage temp.

2-8°C

SMILES string

[H]n1c2ccc3ccccc3c2c4c1ccc5ccccc45

InChI

1S/C20H13N/c1-3-7-15-13(5-1)9-11-17-19(15)20-16-8-4-2-6-14(16)10-12-18(20)21-17/h1-12,21H

InChI key

STJXCDGCXVZHDU-UHFFFAOYSA-N

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Analysis Note

For more information please see:
BCR266

Legal Information

BCR is a registered trademark of European Commission

Pictograms

Health hazardExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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K R Mitchell et al.
Molecular carcinogenesis, 32(2), 55-60 (2001-12-18)
Carcinogenic N-heterocyclic aromatic hydrocarbons are formed during the incomplete combustion of fossil fuels as well as cigarette smoke. N-Methyldibenzo[c,g]carbazole (NMeDBC) and 7H-dibenzo[c,g]carbazole (DBC) are members of this group. DBC induces mouse skin and liver tumors, whereas NMeDBC induces only mouse
T O'Brien et al.
Toxicology in vitro : an international journal published in association with BIBRA, 16(3), 235-243 (2002-05-22)
7H-Dibenzo[c,g]carbazole (DBC) is a model N-heterocyclic aromatic compound (NHA) which is both a hepatotoxin and hepatocarcinogen in rodents. The focus of this investigation was to determine whether human liver cell lines display differential sensitivities to DBC-induced toxicity. Treatment of cell
Zuzana Valovičová et al.
Mutation research, 743(1-2), 91-98 (2012-02-07)
Differences between tissues in the expression of drug-metabolizing enzymes may substantially contribute to tissue-specificity of chemical carcinogens. To verify this hypothesis, the spontaneously immortalized human keratinocytes HaCaT were used, in order to evaluate the genotoxic potential of 7H-dibenzo[c,g]carbazole (DBC), a
G Ericson et al.
Mutation research, 454(1-2), 11-20 (2000-10-18)
The time-course and dose dependent formation of DNA adducts in juvenile northern pike (Esox lucius) following a single exposure to a mixture of benzo[a]pyrene (BaP), benzo[k]fluoranthene (BkF) and 7H-dibenzo[c,g]carbazole (DBC) were investigated by use of the (32)P-postlabelling assay. A complex
O Dorchies et al.
Toxicologic pathology, 29(5), 528-534 (2001-11-07)
The purpose of this work was to investigate the administration of very low but repeated doses of a genotoxic carcinogen and an eventual correlation with cellular DNA synthesis. The compound 7H-dibenzo[c,g]carbazole is a genotoxic carcinogen in the mouse liver and

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