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Salidroside

analytical standard

Synonym(s):

2-(4-Hydroxyphenyl)ethyl β−D-glucopyranoside, p-Hydroxyphenethyl glucopyranoside, Rhodioloside, Rhodosin, Tyrosol a-(β-D-glucopyranoside)

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About This Item

Empirical Formula (Hill Notation):
C14H20O7
CAS Number:
10338-51-9
Molecular Weight:
300.30
MDL number:
MFCD00210553
UNSPSC Code:
85151701
PubChem Substance ID:
329756416
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥98.0% (HPLC)

optical activity

[α]/D -29±2°, c = 0.5 in methanol

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

SMILES string

OC[C@H]1O[C@@H](OCCc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C14H20O7/c15-7-10-11(17)12(18)13(19)14(21-10)20-6-5-8-1-3-9(16)4-2-8/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1

InChI key

ILRCGYURZSFMEG-RKQHYHRCSA-N

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General description

Salidroside is one of the major phenolic glycoside extracted from Rhodiola rosea L(, which can show a broad-spectrum of pharmacological properties like anti-aging, anti-oxidant, anti-cancer and anti-inflammation.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Salidroside, the 8-O-β-D-glucoside of tyrosol, is the main bioactive component of Rhodiola species and is found mainly in the plant roots. It is biosynthesised in the tyrosine metabolism, with glucosylation of tyrosol being the final step. It has been reported to be neuroprotective and one of the compounds responsible for the antidepressant and anxiolytic actions of Rhodiola rosea.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM4309
BCCL2086
BCCH2071
BCCD9981
BCCC1278

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A Panossian et al.
Phytotherapy research : PTR, 19(10), 819-838 (2005-11-02)
Plant adaptogens are compounds that increase the ability of an organism to adapt to environmental factors and to avoid damage from such factors. The beneficial effects of multi-dose administration of adaptogens are mainly associated with the hypothalamic-pituitary-adrenal (HPA) axis, a
Jin-Kang Zhang et al.
PloS one, 8(2), e57251-e57251 (2013-02-26)
Oxidative stress is a pivotal pathogenic factor for bone loss in mouse model. Salidroside, a phenylpropanoid glycoside extracted from Rhodiola rosea L, exhibits potent antioxidative effects. In the present study, we used an in vitro oxidative stress model induced by
Ken Yu-Zhong Zheng et al.
European journal of pharmacology, 679(1-3), 34-39 (2012-02-09)
Rhodiolae Crenulatae Radix et Rhizoma (Rhodiola), the root and rhizome of Rhodiola crenulata (Hook. f. et Thoms.) H. Ohba, has been used as a traditional Chinese medicine (TCM) to increase the body resistance to mountain sickness in preventing hypoxia; however
Shu Yu et al.
Cellular and molecular neurobiology, 28(8), 1067-1078 (2008-05-16)
The hypoglycemia and serum limitation-induced cell death in cultured PC12 cells represents a useful in vitro model for the study of brain ischemia and neurodegenerative disorders. Salidroside is a phenylpropanoid glycoside isolated from Rhodiola rosea L., a traditional Chinese medicinal
Li Zhang et al.
European journal of pharmacology, 564(1-3), 18-25 (2007-03-14)
Oxidative stress plays an important role in Alzheimer's disease and other neurodegenerative disorders. Salidroside, a phenylpropanoid glycoside isolated from Rhodiola rosea L, shows potent antioxidant property. In this paper, the neuroprotective effects of salidroside on hydrogen peroxide (H2O2)-induced apoptosis in
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