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Calcium ionophore II

Selectophore™, function tested

Synonym(s):

N,N,N′,N′-Tetra[cyclohexyl]diglycolic acid diamide, N,N,N′,N′-Tetracyclohexyl-3-oxapentanediamide, ETH 129

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About This Item

Empirical Formula (Hill Notation):
C28H48N2O3
CAS Number:
74267-27-9
Molecular Weight:
460.69
Beilstein:
6491651
MDL number:
MFCD00043337
UNSPSC Code:
26111700
PubChem Substance ID:
329752116
NACRES:
NB.61

grade

for ion-selective electrodes

Quality Level

200

product line

Selectophore™

form

solid

quality

function tested

SMILES string

O=C(COCC(=O)N(C1CCCCC1)C2CCCCC2)N(C3CCCCC3)C4CCCCC4

InChI

1S/C28H48N2O3/c31-27(29(23-13-5-1-6-14-23)24-15-7-2-8-16-24)21-33-22-28(32)30(25-17-9-3-10-18-25)26-19-11-4-12-20-26/h23-26H,1-22H2

InChI key

URAUKAJXWWFQSU-UHFFFAOYSA-N

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General description

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Application

Selected application examples
Calcium ionophore II (ETH 129) was used in preparing calcium selective minielectrodes which are used in determination of dissociation constant (Kd).
Suitable for intracellular calcium measurements.
Lipophilic ionophore for Ca2+-selective electrodes with detection limit in the sub-nanomolar range. Extremely efficient carrier of Ca2+-ions; induces a selectivity in membranes for Ca2+ over Mg2+ by a factor of about 104.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

Selectophore is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
60824/2
AR060824/2
AR60824/2
060824/2V
060824/2

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Xiaoxue Liu et al.
Mikrochimica acta, 187(9), 525-525 (2020-08-29)
Ultrathin metallic WS2 (M-WS2) nanosheets and semiconductive WS2 (S-WS2) nanosheets were exfoliated and for the first time employed as ion-to-electron transducing layer to construct an all-solid-state ion-selective electrode. Importantly, we found that the transducing efficiency of WS2 nanosheet-based solid-contact layer is
Scott T Keene et al.
Advanced healthcare materials, 8(24), e1901321-e1901321 (2019-11-13)
Wearable health monitoring has garnered considerable interest from the healthcare industry as an evolutionary alternative to standard practices with the ability to provide rapid, off-site diagnosis and patient-monitoring. In particular, sweat-based wearable biosensors offer a noninvasive route to continuously monitor
L Hove-Madsen et al.
Biophysical journal, 63(1), 89-97 (1992-07-01)
We have examined the binding of the fluorescent Ca indicator indo-1 to cellular protein in permeabilized ventricular myocytes and also to soluble and particulate myocyte protein. Using either a filtration technique or equilibrium dialysis, and conditions similar to those in
Iwona Bedlechowicz-Sliwakowska et al.
Analytical and bioanalytical chemistry, 385(8), 1477-1482 (2006-07-19)
In this work, ion-selective electrodes for calcium ion were investigated. Two ionophores were used in the membranes: ETH 1001 and ETH 129. An internal filling solution buffered for primary ion was used that allowed the lower detection limit to be
Yi Yuan et al.
Analytical chemistry, 76(18), 5570-5578 (2004-09-15)
Chronoamperometry was carried out at liquid/liquid interfaces supported at the tip of micropipet electrodes for direct determination of the diffusion coefficient of a species in the outer solution. The diffusion coefficient was used for subsequent determination of the transferred charges
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