840857P

16:0-18:1 PA

powder

• Synonym(s): 1-hexadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phosphate (sodium salt); POPA; PA(16:0/18:1(9Z)); 110616
• Empirical Formula (Hill Notation): C₃₇H₇₀O₈PNa
• CAS Number: 169437-35-8
• Molecular Weight: 696.91
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• description: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphate (sodium salt)
• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 2 × 100 mg (840857P-200mg); pkg of 5 × 100 mg (840857P-500mg); pkg of 1 × 25 mg (840857P-25mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• lipid type: cardiolipins; phospholipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]
• InChI: 1S/C37H71O8P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(39)45-35(34-44-46(40,41)42)33-43-36(38)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h17-18,35H,3-16,19-34H2,1-2H3,(H2,40,41,42);/q;+1/p-1/b18-17-;/t35-;/m1./s1
• InChI key: PPYXMAJBOKWTQX-RYRMQHSSSA-M

Description

General description

Phosphatidic acid (PA), the smallest and simplest phospholipid is produced from phosphatidylcholine with the help of phospholipase D. This glycerophospholipid is an ester of glycerol, which possess two long-chain fatty acids (LCFAs) at C1 and C2 and phosphoric acid at C3 positions.

Application

16:0-18:1 PA is suitable for use

• in liposomes preparation
• for lipid extraction of mitochondria
• to generate multilamellar phospholipid vesicles

Biochem/physiol Actions

Phosphatidic acid (PA) may induce negative curvature in the cytoplasmic leaflet of the plasma membrane, which enables the development of the hemi fusion intermediates, that is essential for the fusion of two membranes.

Packaging

5 mL Clear Glass Sealed Ampule (840857P-200mg)

5 mL Clear Glass Sealed Ampule (840857P-25mg)

5 mL Clear Glass Sealed Ampule (840857P-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable