Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
58150AST
CHIRALPAK® AGP (5 μm) HPLC Columns
L × I.D. 10 cm × 4 mm, HPLC Column
Synonym(s):
AGP Chiral Chromatography Column
About This Item
Recommended Products
Product Name
CHIRALPAK® AGP HPLC Column, 5 μm particle size, L × I.D. 10 cm × 4 mm
material
stainless steel column
Agency
suitable for USP L41
product line
CHIRALPAK®
packaging
pkg of 1 ea
manufacturer/tradename
CHIRALPAK®
parameter
137 bar pressure (2000 psi)
20-30 °C temperature
40 °C max. temp.
technique(s)
HPLC: suitable
L × I.D.
10 cm × 4 mm
matrix
fully porous particle
matrix active group
glycoprotein, alpha1- phase
particle size
5 μm
operating pH
2-8
separation technique
chiral
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General description
Features:
- Direct reversed phase resolution of chiral molecules
- Stable with a variety of organic modifiers
- Available in analytical and semi-preparative sizes
(1) Hermansson, J. Direct liquid chromatographic resolution of racemic drugs using a1-acid glycoprotein as the chiral stationary phase. J. Chromatogr. A, 1983, 269, 71-80.
Application
- Enantiomeric methadone quantitation on real post-mortem dried matrix spots samples: Comparison of liquid chromatography and supercritical fluid chromatography coupled to mass spectrometry.: This study explores the application of enantioselective liquid chromatography techniques, including the use of CHIRALPAK® AGP, for the quantitation of methadone enantiomers on dried matrix spots, contributing to forensic toxicology and analytical chemistry (Mueller et al., 2021).
- Enantiomeric Separation of Dioxopromethazine and its Stereoselective Pharmacokinetics in Rats by HPLC-MS/MS.: This research demonstrates the utility of chiral stationary phases, such as CHIRALPAK® AGP, for separating enantiomers of pharmaceutical compounds, providing insights into stereoselective pharmacokinetics critical for drug development and clinical pharmacology (Lun et al., 2021).
- Evaluation of R- (-) and S- (+) Clenbuterol enantiomers during a doping cycle or continuous ingestion of contaminated meat using chiral liquid chromatography by LC-TQ-MS.: This article details the application of chiral liquid chromatography, potentially involving CHIRALPAK® AGP columns, to distinguish between therapeutic use and contamination sources of clenbuterol, addressing challenges in sports doping analysis (Dolores et al., 2019).
Legal Information
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdfHelpful?
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