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RAB1092

Sigma-Aldrich

Human TSG-6 ELISA Kit

for cell culture supernatants, plasma, and serum samples

Synonym(s):

Hyaluronate-binding protein, TSG-6, Tumor necrosis factor-inducible gene 6 protein 

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type cell culture supernatant(s)
sample type serum sample(s)
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.2 ng/ml

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... TNFAIP6(7130)

Related Categories

General description

This ELISA antibody pair detects human TSG-6. Other species not yet determined.

Application

Human TSG-6 ELISA Kit has been used to determine galectin G3 and intermediate metabolites level.

Biochem/physiol Actions

Tumor necrosis factor (TNF)-α–stimulated gene 6 protein (TSG-6) has been implicated in regulation of cell-cell and cell-matrix interactions during inflammation and tumorigenesis. TSG-6 possess anti-inflammatory properties. It is also known to reduce inflammatory reactions triggered by ischemia in the heart. Thus, it might have a potential role in treating heart disease with other cells such as skeletal myoblasts, fetal myoblasts and embryonic stem cells.

Other Notes

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

Pictograms

Corrosion
GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF-?B signaling in resident .
Hosoo , et al.
Blood, 118, 330-338 (2011)
Hao Yang et al.
Journal of neuroinflammation, 17(1), 154-154 (2020-05-13)
Neuroinflammation plays a vital role in the development and maintenance of neuropathic pain. Recent evidence has proved that bone marrow mesenchymal stem cells (BMSCs) can inhibit neuropathic pain and possess potent immunomodulatory and immunosuppressive properties via secreting a variety of
The value of determination of galectin-3 and midkine in serum of patients with thyroid cancer for the evaluation of tumor condition.
Liu Y, et al.
Journal of Hainan Medical College, 3, 38-38 (2017)
S Keisin Wang et al.
The Journal of surgical research, 220, 311-319 (2017-11-29)
The formation of abdominal aortic aneurysms (AAA) is characterized by a dominance of proinflammatory forces that result in smooth muscle cell apoptosis, extracellular matrix degradation, and progressive diameter expansion. Additional defects in the antiinflammatory response may also play a role
Haggai Kaspi et al.
Stem cell research & therapy, 12(1), 72-72 (2021-01-21)
One of the most severe complications of the current COVID-19 pandemic is acute respiratory distress syndrome (ARDS). ARDS is caused by increased amounts of pro-inflammatory cytokines, leading to lung damage and loss of lung function. There are currently no effective
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