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90916

Sigma-Aldrich

ZnAF-2F

≥95.0% (HPCE)

Synonym(s):

6-{2-[Bis(2-pyridylmethyl)amino]ethylamino}-2′,7′-difluorofluorescein

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About This Item

Empirical Formula (Hill Notation):
C34H26F2N4O5
CAS Number:
443302-09-8
Molecular Weight:
608.59
MDL number:
MFCD08277019
UNSPSC Code:
12352101
PubChem Substance ID:
57653416
NACRES:
NC.07

Quality Level

100

Assay

≥95.0% (HPCE)

form

powder

fluorescence

λex 492 nm; λem 517 nm in PBS, Zn2+

storage temp.

−20°C

SMILES string

OC(=O)c1ccc(NCCN(Cc2ccccn2)Cc3ccccn3)cc1C4=C5C=C(F)C(=O)C=C5Oc6cc(O)c(F)cc46

InChI

1S/C34H26F2N4O5/c35-27-14-25-31(16-29(27)41)45-32-17-30(42)28(36)15-26(32)33(25)24-13-20(7-8-23(24)34(43)44)39-11-12-40(18-21-5-1-3-9-37-21)19-22-6-2-4-10-38-22/h1-10,13-17,39,41H,11-12,18-19H2,(H,43,44)

InChI key

HPADXJLXFKDPBV-UHFFFAOYSA-N

Related Categories

Application

suitable for the fluorimetric detection of Zn2+

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Tahereh Ziglari et al.
Inhalation toxicology, 32(2), 86-95 (2020-03-29)
Background: While the role of lysosomal membrane permeabilization (LMP) in NP-induced inflammatory responses has been recognized, the underlying mechanism of LMP is still unclear. The assumption has been that zinc oxide (ZnO)-induced LMP is due to Zn2+; however, little is
Tomoya Hirano et al.
Journal of the American Chemical Society, 124(23), 6555-6562 (2002-06-06)
The development and cellular applications of novel fluorescent probes for Zn2+, ZnAF-1F, and ZnAF-2F are described. Fluorescein is used as a fluorophore of ZnAFs, because its excitation and emission wavelengths are in the visible range, which minimizes cell damage and

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