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13142

Sigma-Aldrich

Magnesium sulfate heptahydrate

99.5-100.5% (calc. to the dried substance), meets analytical specification of Ph. Eur., BP,USP, FCC

Synonym(s):

Epsom salts

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About This Item

Linear Formula:
MgSO4 · 7H2O
CAS Number:
Molecular Weight:
246.47
EC Number:
MDL number:
UNSPSC Code:
12352302
eCl@ss:
38030409
PubChem Substance ID:
NACRES:
NA.21

vapor density

<0.01 (vs air)

Quality Level

vapor pressure

<0.1 mmHg ( 20 °C)

Assay

99.5-100.5% (calc. to the dried substance)

form

powder or crystals

quality

meets analytical specification of Ph. Eur., BP,USP, FCC

impurities

acidity or alkalinity, in accordance
organic volatile impurities, complies (GC)
residual solvents, complies
≤0.001 ppm heavy metals (as Pb)
≤0.004% free alkali (as MgO)
≤0.01% free acid (as H2SO4)

loss

48.0-52.0% loss on drying, 450 °C

pH

5.0-9.2 (25 °C, 5%)

anion traces

chloride (Cl-): ≤150 mg/kg

cation traces

As: ≤2 ppm
Fe: ≤20 ppm
Pb: ≤4 ppm
Se: ≤30 ppm

suitability

complies for appearance of solution

SMILES string

O.O.O.O.O.O.O.[Mg++].[O-]S([O-])(=O)=O

InChI

1S/Mg.H2O4S.7H2O/c;1-5(2,3)4;;;;;;;/h;(H2,1,2,3,4);7*1H2/q+2;;;;;;;;/p-2

InChI key

WRUGWIBCXHJTDG-UHFFFAOYSA-L

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General description

Magnesium sulfate heptahydrate is the hydrated salt of magnesium. The spin-Hamiltonian parameters of the (Cu(H2O)6)2+ complex in magnesium sulfate heptahydrate have been determined by electron spin resonance (ESR) spectral studies. Raman spectra of 10 hydrated and anhydrous forms of magnesium sulfates have been reported. Their crystal structure and space groups have been evaluated by Raman and XRD (X-ray diffraction) studies.

Application


  • Optimization of the fermentation media and growth conditions of Bacillus velezensis BHZ-29: This research utilizes Magnesium sulfate heptahydrate as a crucial micronutrient in the optimized growth medium for Bacillus velezensis, enhancing its bioactivity and efficacy in agricultural biocontrol applications (Shi et al., 2024).

  • Research on and Model Analysis of Flexural Mechanical Properties of Basic Magnesium Sulfate Cement Concrete Beams: The study focuses on the use of Magnesium sulfate heptahydrate in the production of magnesium sulfate cement, a material noted for its improved flexural strength and durability, which is critical for sustainable construction practices (Mei et al., 2024).

  • Antimicrobial Activity of Bacillus amyloliquefaciens BS4 against Gram-Negative Pathogenic Bacteria: Magnesium sulfate heptahydrate is used here as a component of the growth medium to enhance the production of antimicrobial compounds, illustrating its role in supporting microbial activity with potential applications in biotechnology and pharmaceuticals (Palacios-Rodriguez et al., 2024).

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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ESR studies of (Cu(H2O)6)2+ in magnesium sulfate heptahydrate.
Radhakrishna S and Bhaskar Rao T.
Journal of Magnetic Resonance, 32(1), 71-81 (1978)
Sulfates on Mars: A systematic Raman spectroscopic study of hydration states of magnesium sulfates.
Wang A, et al.
Geochimica et Cosmochimica Acta, 70(24), 6118-6135 (2006)
Ran D Goldman et al.
Pediatrics, 132(6), e1634-e1641 (2013-11-28)
Vaso-occlusive episodes (VOEs) are the most common complication of sickle cell disease in children. Treatment with magnesium seems to improve cellular hydration and may result in reduced vaso-occlusion. This study aimed to determine if intravenous (IV) magnesium sulfate (MgSO4) reduces
Oluwakemi Badaki-Makun et al.
Pediatric blood & cancer, 61(6), 1049-1054 (2014-01-21)
Multiple recent Sickle Cell Disease studies have been terminated due to poor enrollment. We developed methods to overcome past barriers and utilized these to study the efficacy and safety of intravenous magnesium for vaso-occlusive crisis (VOC). We describe the methods
E S Bain et al.
BJOG : an international journal of obstetrics and gynaecology, 121(5), 595-603 (2014-01-07)
To evaluate a slower (compared with a standard) infusion rate of the loading dose of magnesium sulphate for preterm fetal neuroprotection as a strategy to reduce maternal adverse effects. Randomised controlled trial. South Australian maternity hospital. Fifty-one women at <30

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