QBD10175

m-dPEG^®₄-amine

• Synonym(s): 2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethylamine, 3,6,9,12-Tetraoxatridecylamine, Polyethylene glycol, Triethylene glycol 2-aminoethyl methyl ether
• Empirical Formula (Hill Notation): C₉H₂₁NO₄
• CAS Number: 85030-56-4
• Molecular Weight: 207.27
• MDL number: MFCD11041099
• UNSPSC Code: 12352116
• PubChem Substance ID: 329823883
• NACRES: NA.22

Properties

• Assay: >90%
• form: solid or viscous liquid
• reaction suitability: reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: carboxyl reactive
• polymer architecture: shape: linear; functionality: monofunctional
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: NCCOCCOCCOCCOC
• InChI: 1S/C9H21NO4/c1-11-4-5-13-8-9-14-7-6-12-3-2-10/h2-10H2,1H3
• InChI key: DQTQYVYXIOQYGN-UHFFFAOYSA-N

Description

Features and Benefits

m-dPEG^®₄-amine provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG^® molecules are hydrophilic and non-immunogenic of exact length. There are four repeat units in this linear dPEG^® chain. Modification with m-dPEG^® reagent can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG^®₄-amine reacts with carboxylic acids and active esters.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable