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16230

Sigma-Aldrich

4-Bromoaniline

≥99.0% (GC)

Synonym(s):

1-Amino-4-bromobenzene, p-Bromoaniline

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About This Item

Linear Formula:
BrC6H4NH2
CAS Number:
Molecular Weight:
172.02
Beilstein:
742031
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

≥99.0% (GC)

form

solid

mp

56-62 °C (lit.)
63-65 °C

solubility

ethanol: soluble 0.5 g/10 mL, clear, colorless to almost colorless

SMILES string

Nc1ccc(Br)cc1

InChI

1S/C6H6BrN/c7-5-1-3-6(8)4-2-5/h1-4H,8H2

InChI key

WDFQBORIUYODSI-UHFFFAOYSA-N

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General description

Photocatalytic degradation of 4-bromoaniline over ZnO or TiO2 (anatase and rutile) has been investigated in a photocatalytic reactor.

Application

4-Bromoaniline was used as carbon and nitrogen supplement in the culture medium of Moraxella sp. strain G.

Biochem/physiol Actions

4-Bromoaniline reduces gluconeogenesis in renal cortical slices obtained from the kidneys of untreated, male Fischer 344 rats.

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Fernanda Raphael Escobar Gimenes et al.
PloS one, 15(11), e0241849-e0241849 (2020-11-20)
To identify the types of nasogastric/nasoenteric tube (NGT/NET)-related adverse events and to analyze the degree of harm and the factors associated with mechanical device-related complications. A prospective cohort study was conducted from October 2017 to April 2019 in seven Brazilian
Mohammad Hossein Habibi et al.
Annali di chimica, 94(5-6), 421-428 (2004-07-29)
Photocatalytic degradation of aqueous solution of aniline derivatives such as ortho-nitroaniline (ONA), meta-nitroaniline (MNA), para-nitroaniline (PNA), 4-bromoaniline (4-BrA) and 2-chloroaniline (2-ClA) were carried out over ZnO or TiO2 (anatase and rutile) in a photocatalytic reactor. The observed results revealed that
S K Hong et al.
Toxicology letters, 114(1-3), 125-133 (2000-03-14)
Haloanilines are widely used as chemical intermediates in the manufacture of pesticides, dyes and drugs. The purpose of this study was to examine the in vitro nephrotoxic effects of the four 4-haloaniline and four 3,5-dihaloaniline isomers using renal cortical slices
Hilary Major et al.
Rapid communications in mass spectrometry : RCM, 17(1), 76-80 (2002-12-13)
The metabolic fate of 4-bromoaniline (4-BrA) was investigated following intraperitoneal administration to the rat at 50 mg kg(-1), using high-performance liquid chromatography/time-of-flight tandem mass spectrometry (HPLC/TOF-MS/MS). Up to five metabolites were detected in urine that correspond to isomeric pentose conjugates
J K Nicholson et al.
The Analyst, 125(2), 235-236 (2000-05-23)
The use of HPLC-ICP-MS for the profiling and quantification of the metabolites of 4-bromoaniline following reversed-phase gradient chromatography is demonstrated. In the 0-8 h post dose sample, which contained the highest concentrations of compound-related material, it was possible to detect

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