P4247

Anti-Potassium Channel K_v1.3 (extracellular)−FITC antibody produced in rabbit

affinity isolated antibody, lyophilized powder

• Synonym(s): Anti-Kcna3, Anti-Voltage-gated Potassium Channel K_V1.3
• MDL number: MFCD06798515
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 200
• conjugate: FITC conjugate
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• species reactivity: rat, human, mouse
• technique(s): flow cytometry: 0.5-5 μg/test using Jurkat T-cells; western blot: 1:200-1:500 using rat brain membranes
• UniProt accession no.: P22001
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... KCNA3(3738) ; mouse ... Kcna3(16491) ; rat ... Kcna3(29731)

Description

General description

The (K⁺) channel family has been sub-grouped in to 2 TM, 4 TM and 6 TM (K⁺) channels based on the number of transmembrane domains. The voltage-gated Potassium or (Kv) channels belong to the 6 TM (K⁺) channel family and are expressed mainly in hematopoietic cells such as T and B lymphocytes, macrophages and natural killer cells. (Kv)1.3 facilitates cell proliferation and can also regulate the immune system. Genetic alterations in (Kv) 1.3 lead to epilepsy, episodic ataxia/myokymia, and episodic cardiac arrhythmia (the long QT syndrome). Anti-potassium channel (Kv) 1.3 (extracellular)−FITC antibody can be used for western blotting of rat brain membranes. Rabbit anti- potassium channel (Kv) 1.3 (extracellular) antibodies reacts specifically with rat and human (Kv) 1.3.

Immunogen

synthetic peptide corresponding to residues 211-224 of human K_V1.3. Rat and mouse are 12/14 residues identical.

Application

Anti-potassium channel (Kv) 1.3 (extracellular)−FITC antibody can be used in immunoblotting and flow cytometry.

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, 1% bovine serum albumin, 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable