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Key Documents

30885

Supelco

Thiourea

≥99.999% (metals basis)

Synonym(s):

Sulfourea, Thiocarbamide

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About This Item

Linear Formula:
NH2CSNH2
CAS Number:
Molecular Weight:
76.12
Beilstein:
605327
EC Number:
MDL number:
UNSPSC Code:
41116105
PubChem Substance ID:
NACRES:
NA.24

Quality Level

Assay

≥99.999% (metals basis)

mp

170-176 °C (lit.)

cation traces

Ag: ≤0.01 mg/kg
Al: ≤0.05 mg/kg
As: ≤0.05 mg/kg
Au: ≤0.01 mg/kg
Ba: ≤0.05 mg/kg
Be: ≤0.05 mg/kg
Bi: ≤0.01 mg/kg
Ca: ≤2 mg/kg
Cd: ≤0.01 mg/kg
Ce: ≤0.01 mg/kg
Co: ≤0.01 mg/kg
Cr: ≤0.05 mg/kg
Cs: ≤0.01 mg/kg
Cu: ≤0.01 mg/kg
Dy: ≤0.01 mg/kg
Er: ≤0.01 mg/kg
Eu: ≤0.01 mg/kg
Fe: ≤0.5 mg/kg
Ga: ≤0.01 mg/kg
Gd: ≤0.01 mg/kg
Ge: ≤0.01 mg/kg
Hf: ≤0.01 mg/kg
Hg: ≤0.005 mg/kg
Ho: ≤0.01 mg/kg
In: ≤0.01 mg/kg
Ir: ≤0.01 mg/kg
K: ≤0.2 mg/kg
La: ≤0.01 mg/kg
Li: ≤0.01 mg/kg
Lu: ≤0.01 mg/kg
Mg: ≤0.05 mg/kg
Mn: ≤0.01 mg/kg
Mo: ≤0.01 mg/kg
Na: ≤0.5 mg/kg
Nb: ≤0.01 mg/kg
Nd: ≤0.01 mg/kg
Ni: ≤0.05 mg/kg
Os: ≤0.01 mg/kg
Pb: ≤0.01 mg/kg
Pd: ≤0.05 mg/kg
Pr: ≤0.01 mg/kg
Pt: ≤0.05 mg/kg
Rb: ≤0.01 mg/kg
Re: ≤0.01 mg/kg
Rh: ≤0.01 mg/kg
Ru: ≤0.01 mg/kg
Sb: ≤0.01 mg/kg
Sc: ≤0.05 mg/kg
Se: ≤0.05 mg/kg
Sm: ≤0.01 mg/kg
Sn: ≤0.01 mg/kg
Sr: ≤0.1 mg/kg
Ta: ≤0.01 mg/kg
Tb: ≤0.01 mg/kg
Te: ≤0.01 mg/kg
Th: ≤0.01 mg/kg
Ti: ≤0.05 mg/kg
Tl: ≤0.01 mg/kg
Tm: ≤0.01 mg/kg
U: ≤0.01 mg/kg
V: ≤0.01 mg/kg
W: ≤0.01 mg/kg
Y: ≤0.01 mg/kg
Yb: ≤0.01 mg/kg
Zn: ≤0.05 mg/kg
Zr: ≤0.05 mg/kg

SMILES string

NC(N)=S

InChI

1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)

InChI key

UMGDCJDMYOKAJW-UHFFFAOYSA-N

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Application

Chaotropic agent; strong denaturant. Increases solubility and recovery of proteins
Thiourea is a chaotropic agent; strong denaturant. Increases solubility and recovery of proteins.

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


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Use of thiourea to increase the solubility of membrane proteins in two-dimensional electrophoresis.
Rabilloud T.
Electrophoresis, 19(5), 758-760 (1998)
Proteomic analysis of the human pathogen Trypanosoma cruzi.
Paba J, et al.
Proteomics, 4(4), 1052-1059 (2004)
Denaturation of Globular Proteins I. THE INTERACTION OF UREA AND THIOUREA WITH BOVINE PLASMA ALBUMIN.
Gordon JA and Warren JR
The Journal of Biological Chemistry, 243(21), 5663-5669 (1968)

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