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Sodium dihydrogen phosphate anhydrous

for HPLC LiChropur™

Synonym(s):

Sodium dihydrogen phosphate anhydrous, Sodium biphosphate

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About This Item

Empirical Formula (Hill Notation):
H2NaO4P
CAS Number:
7558-80-7
Molecular Weight:
119.98
MDL number:
MFCD00003527
UNSPSC Code:
41116105
EC Index Number:
231-449-2
NACRES:
NA.21
Pricing and availability is not currently available.

grade

anhydrous

Quality Level

100

technique(s)

HPLC: suitable

pH

4.5 (20 °C, 10 g/L in H2O)

solubility

850 g/L

bulk density

940 kg/m3

application(s)

environmental
food and beverages

format

single component solution

storage temp.

2-30°C

SMILES string

[Na+].[P](=O)([O-])([O-])[O-].[H+].[H+]

InChI

1S/Na.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+1;/p-1

InChI key

AJPJDKMHJJGVTQ-UHFFFAOYSA-M

General description

Sodium dihydrogen phosphate anhydrous iscommonly used in high-performance liquid chromatography (HPLC) as a bufferingagent to control the pH of the mobile phase.[1][2]

Application

Sodium dihydrogen phosphate anhydrous can be used as an a buffering agent:
  • For the mobile phase in RP-HPLC for the simultaneous determination of pyridoxine hydrochloride and meclizine hydrochloride in pharmaceutical formulations.[2]
  • In the heparin hydrolysis.

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Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Prolonged continuous intravenous infusion of the dipeptide L-alanine-L-glutamine significantly increases plasma glutamine and alanine without elevating brain glutamate in patients with severe traumatic brain injury
Nageli M, et al.
Critical Care, 18(4), 1-12 (2014)
A new validated stability indicating RP-HPLC method for simultaneous estimation of pyridoxine hydrochloride and meclizine hydrochloride in pharmaceutical solid dosage forms
Nawaz MS
Chromatography Research International, 2013 (2013)

Articles

Assay of Doxepin Hydrochloride USP Monograph

The FPP Purospher® STAR RP-8e column offers a reliable and consistent assay with strong peak shapes and linearity, ensuring precise quantification.

Assay of Doxepin Hydrochloride USP Monograph

The FPP Purospher® STAR RP-8e column offers a reliable and consistent assay with strong peak shapes and linearity, ensuring precise quantification.

Assay of Doxepin Hydrochloride USP Monograph

The FPP Purospher® STAR RP-8e column offers a reliable and consistent assay with strong peak shapes and linearity, ensuring precise quantification.

Assay of Doxepin Hydrochloride USP Monograph

The FPP Purospher® STAR RP-8e column offers a reliable and consistent assay with strong peak shapes and linearity, ensuring precise quantification.

Questions

1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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