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234140

Sigma-Aldrich

Collagenase Inhibitor I

The Collagenase Inhibitor I controls the biological activity of Collagenase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Synonym(s):

Collagenase Inhibitor I, Z-PDLDA-NHOH

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About This Item

Empirical Formula (Hill Notation):
C22H32N4O6
Molecular Weight:
448.51
UNSPSC Code:
12352200
NACRES:
NA.54

Quality Level

Assay

≥98% (HPLC)

form

solid

potency

1 μM IC50

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

ethanol: 5 mg/mL

shipped in

ambient

storage temp.

−20°C

General description

A potent and specific inhibitor of vertebrate collagenases with IC50 values in the micromolar range.
A potent and specific inhibitor of vertebrate collagenases with IC50 values in the order of 1 µM.

Biochem/physiol Actions

Cell permeable: no
Primary Target
vertebrate collegenases
Product does not compete with ATP.
Reversible: no

Packaging

Packaged under inert gas

Warning

Toxicity: Standard Handling (A)

Sequence

Z-Pro-D-Leu-D-Ala-NHOH

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Odake, S., et al. 1990. Chem. Pharm. Bull. 38, 1007.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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