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217794

Sigma-Aldrich

DL-3-Aminoisobutyric acid

98%, for peptide synthesis

Synonym(s):

α-Methyl-β-alanine

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About This Item

Linear Formula:
NH2CH2CH(CH3)COOH
CAS Number:
Molecular Weight:
103.12
Beilstein:
1720958
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.22

product name

DL-3-Aminoisobutyric acid, 98%

Assay

98%

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

mp

179-182 °C (lit.)

application(s)

peptide synthesis

SMILES string

CC(CN)C(O)=O

InChI

1S/C4H9NO2/c1-3(2-5)4(6)7/h3H,2,5H2,1H3,(H,6,7)

InChI key

QCHPKSFMDHPSNR-UHFFFAOYSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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M Jóźwik et al.
Placenta, 19(7), 531-538 (1998-10-20)
Placental uptake and transport of three nonmetabolizable amino acids with different reactivities for transport systems were studied in sheep under normal physiologic conditions. Methylaminoisobutyric acid (MeAIB), which has specific affinity for the sodium-dependent A system transporters, demonstrated placental concentrative uptake
Y Kurozumi et al.
Acta medica Okayama, 53(1), 13-18 (1999-03-30)
Experimental beta-alaninuria was induced in rats by injection of (aminooxy)acetate (AOA), a potent inhibitor of aminotransferases, in order to elucidate the pathogenesis of hyper-beta-alaninemia. A 27-fold increase of beta-alanine (BALA) excretion was induced by subcutaneous injection of 1 5 mg
P M Zeis et al.
Cytobios, 102(400), 107-113 (2000-07-08)
Previous investigators agree on the increased DNA synthesis and destruction of tissues caused by folic acid (FA) administered parenterally. This study aims to clarify whether DNA degradation due to the destruction of cells and nuclei precedes DNA synthesis following FA
Anja Kittel et al.
Biochemical and biophysical research communications, 430(1), 84-89 (2012-11-17)
Elevated plasma concentrations of the asymmetric (ADMA) and symmetric (SDMA) dimethylarginine have repeatedly been linked to adverse cardiovascular clinical outcomes. Both dimethylarginines can be degraded by alanine-glyoxylate aminotransferase 2 (Agxt2), which is also the key enzyme responsible for the degradation
Karima Begriche et al.
Fundamental & clinical pharmacology, 24(3), 269-282 (2009-09-09)
Beta-aminoisobutyric acid (BAIBA) is a catabolite of thymine and antiretroviral thymine analogues AZT and d4T. We recently discovered that this beta-amino acid is able to enhance fatty acid oxidation and reduce body weight in mice through an increased production of

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