Negative control for the dopamine D4 receptor (DRD4) partial agonist UCSF924.
UCSF924NC (Compound 9-6-16; ZINC000091707446) is the recommended negative control compound for the high-affinity dopamine D4 receptor (DRD4) partial agonist UCSF924 (Compound 9-6-24; ZINC000091726127). UCSF924NC exhibits a 1/2500-fold reduced D4 affinity when compared with that of UCSF924.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Science (New York, N.Y.), 358(6361), 381-386 (2017-10-21)
Dopamine receptors are implicated in the pathogenesis and treatment of nearly every neuropsychiatric disorder. Although thousands of drugs interact with these receptors, our molecular understanding of dopaminergic drug selectivity and design remains clouded. To illuminate dopamine receptor structure, function, and
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