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Key Documents

H4148

Sigma-Aldrich

DL-β-Hydroxymyristic acid

≥98%

Synonym(s):

3-Hydroxytetradecanoic acid

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About This Item

Empirical Formula (Hill Notation):
C14H28O3
CAS Number:
Molecular Weight:
244.37
MDL number:
UNSPSC Code:
12352211
PubChem Substance ID:
NACRES:
NA.25

biological source

synthetic (organic)

Quality Level

Assay

≥98%

form

powder

functional group

carboxylic acid

lipid type

saturated FAs

shipped in

ambient

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCC(O)CC(O)=O

InChI

1S/C14H28O3/c1-2-3-4-5-6-7-8-9-10-11-13(15)12-14(16)17/h13,15H,2-12H2,1H3,(H,16,17)

InChI key

ATRNZOYKSNPPBF-UHFFFAOYSA-N

Biochem/physiol Actions

DL-β-Hydroxymyristic acid (3-HTA) is a mixture of D- and L-β-hydroxymyristic acid enantiomers. 3-Hydroxytetradecanoic acids are used to study their roles in biological processes such as oxidative stress, inflammation and insulin resistance. 3-HTA is also used in endotoxin and lipid A research.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Pauline Grimm et al.
The British journal of nutrition, 123(4), 372-382 (2019-11-07)
Starchy diets can induce hindgut dysbiosis in horses. The present study evaluated the impact of a yeast (Saccharomyces cerevisiae) and microalgae (Aurantiochytrium limacinum) supplementation on caecal, colonic and faecal microbial ecosystem and on blood inflammatory parameters of horses fed high-fibre
K Tanamoto
Advances in experimental medicine and biology, 256, 203-213 (1990-01-01)
New quantitative method for the detection of minute amounts of endotoxin has been developed using 3-hydroxytetradecanoic acid as a chemical marker. After converting 3-hydroxytetradecanoic acid to methyl ester, it was coupled with a fluorescent probe, anthracene-9-carboxyl chloride, obtained by chlorization
Wenkuan Liu et al.
Applied microbiology and biotechnology, 76(5), 1153-1159 (2007-08-02)
Medium-chain-length polyhydroxyalkanoates (mcl-PHA) consisting of 3-hydroxyhexanoate (HHx), 3-hydroxyoctanoate (HO), 3-hydroxydecanoate, 3-hydroxydodecanoate, and high-content 3-hydroxytetradecanoate (HTD) was produced by knockout mutant Pseudomonas putida KT2442 termed P. putida KTOY06. When grown on 6 to14 g/L single-carbon-source tetradecanoic acid, P. putida KTOY06, which
A S Soydan et al.
Mediators of inflammation, 2006(5), 64980-64980 (2007-03-30)
Beta-hydroxy fatty acids are a major component of lipid A moiety of lipopolysaccharide. We aimed to investigate the role of free beta-hydroxy fatty acids on inflammation, as well as to evaluate their effects on cytokine release from human blood cells
Anelise M Tonin et al.
Neurochemistry international, 56(8), 930-936 (2010-04-13)
Accumulation of long-chain 3-hydroxy fatty acids is the biochemical hallmark of long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) and mitochondrial trifunctional protein (MTP) deficiencies. These disorders are clinically characterized by neurological symptoms, such as convulsions and lethargy, as well as by cardiomyopathy and

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