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N5785

Sigma-Aldrich

L-(−)-Norepinephrine (+)-bitartrate salt monohydrate

meets USP testing specifications

Synonym(s):

L-(−)-Noradrenaline (+)-bitartrate salt monohydrate

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About This Item

Empirical Formula (Hill Notation):
C8H11NO3 · C4H6O6 · H2O
CAS Number:
108341-18-0
Molecular Weight:
337.28
MDL number:
MFCD00150449
UNSPSC Code:
51391722
PubChem Substance ID:
24897754
NACRES:
NA.21

Agency

USP/NF
meets USP testing specifications

Quality Level

200

form

solid

application(s)

pharmaceutical (small molecule)

SMILES string

O.O[C@H]([C@@H](O)C(O)=O)C(O)=O.NC[C@H](O)c1ccc(O)c(O)c1

InChI

1S/C8H11NO3.C4H6O6.H2O/c9-4-8(12)5-1-2-6(10)7(11)3-5;5-1(3(7)8)2(6)4(9)10;/h1-3,8,10-12H,4,9H2;1-2,5-6H,(H,7,8)(H,9,10);1H2/t8-;1-,2-;/m01./s1

InChI key

LNBCGLZYLJMGKP-LUDZCAPTSA-N

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Related Categories

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H300 + H310

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Oral

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000319569
0000319570
0000319568
SLCM1982
SLCF1769

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Pooja R Patel et al.
Journal of bioanalysis & biomedicine, 7(3), 75-80 (2015-07-15)
To determine the role of norepinephrine (NE) on DNA damage and reactive oxygen species (ROS) generation in ovarian surface epithelial cells. Non-tumorigenic, immortalized ovarian surface epithelial cells were treated with NE, bleomycin, and bleomycin followed by NE. The comet assay
Asuka Inoue et al.
Cell, 177(7), 1933-1947 (2019-06-05)
Heterotrimetic G proteins consist of four subfamilies (Gs, Gi/o, Gq/11, and G12/13) that mediate signaling via G-protein-coupled receptors (GPCRs), principally by receptors binding Gα C termini. G-protein-coupling profiles govern GPCR-induced cellular responses, yet receptor sequence selectivity determinants remain elusive. Here
Alicia Villacampa et al.
Aging and disease (2024-07-16)
Premature vascular aging and endothelial cell senescence are major risk factors for cardiovascular diseases and atherothrombotic disturbances, which are main complications of both acute and long COVID-19. The S protein of SARS-CoV2, which acts as the receptor binding protein for
Kanako Iwasaki et al.
Frontiers in neuroscience, 12, 535-535 (2018-08-23)
Sleep/wake behavior is regulated by distinct groups of neurons, such as dopaminergic, noradrenergic, and orexinergic neurons. Although monoaminergic neurons are usually considered to be wake-promoting, the role of serotonergic neurons in sleep/wake behavior remains inconclusive because of the effect of
Kai Jiao et al.
Scientific reports, 6, 30085-30085 (2016-07-28)
This study tested whether activation of adrenoreceptors in chondrocytes has roles in degenerative remodelling of temporomandibular joint (TMJ) and to determine associated mechanisms. Unilateral anterior crossbite (UAC) was established to induce TMJ degeneration in rats. Saline vehicle, α2- and β-adrenoreceptor
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