W246700

Eugenol

≥98%, FCC, FG

• Synonym(s): 2-Methoxy-4-(2-propenyl)phenol, 4-Allyl-2-methoxyphenol, 4-Allylguaiacol
• Linear Formula: 4-(H₂C=CHCH₂)C₆H₃-2-(OCH₃)OH
• CAS Number: 97-53-0
• Molecular Weight: 164.20
• FEMA Number: 2467
• Beilstein: 1366759
• EC Number: 202-589-1
• Council of Europe no.: 171
• MDL number: MFCD00008654
• UNSPSC Code: 12164502
• PubChem Substance ID: 24901114
• Flavis number: 4.003
• NACRES: NA.21

Properties

• biological source: synthetic
• Quality Level: 400
• grade: FG; Halal; Kosher
• Agency: meets purity specifications of JECFA
• reg. compliance: EU Regulation 1334/2008 & 178/2002; FCC; FDA 21 CFR 117; FDA 21 CFR 177.2800
• Assay: ≥98%
• form: liquid
• refractive index: n20/D 1.541 (lit.)
• bp: 254 °C (lit.)
• mp: −12-−10 °C (lit.)
• density: 1.067 g/mL at 25 °C (lit.)
• application(s): flavors and fragrances
• Documentation: see Safety & Documentation for available documents
• food allergen: no known allergens
• Organoleptic: clove; woody; spicy; sweet
• SMILES string: COc1cc(CC=C)ccc1O
• InChI: 1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3
• InChI key: RRAFCDWBNXTKKO-UHFFFAOYSA-N
• Gene Information: human ... UGT1A4(54657)

Description

General description

Eugenol is one of the key volatile constituents of cinnamon and clove oils. It is also the active component of Ocimum sanctum oil, reported to be responsible for its anthelmintic activity.

Application

• Lyophilized Emulsions of Thymol and Eugenol Essential Oils Encapsulated in Cellulose.: Researchers developed lyophilized emulsions of thymol and eugenol essential oils encapsulated in cellulose. This encapsulation method improves the stability and controlled release of these essential oils, highlighting their potential for various industrial applications, including food preservation and pharmaceuticals (Shlosman et al., 2024).


• Insights from Syzygium aromaticum Essential Oil: Encapsulation, Characterization, and Antioxidant Activity.: This paper explores the encapsulation and characterization of Syzygium aromaticum essential oil, which contains eugenol as a major component. The study focuses on its antioxidant activity, demonstrating the potential health benefits and applications in pharmaceuticals and nutraceuticals (Mergulhão et al., 2024).


• Essential Oil Constituents as Anti-Inflammatory and Neuroprotective Agents: An Insight through Microglia Modulation.: This review discusses the anti-inflammatory and neuroprotective properties of essential oil constituents, including eugenol. It highlights the mechanisms through which eugenol modulates microglia, suggesting its potential therapeutic applications in treating neuroinflammatory conditions (Stojanovic et al., 2024).


• Improvement in the Sustained-Release Performance of Electrospun Zein Nanofibers via Crosslinking Using Glutaraldehyde Vapors.: The study investigates the sustained-release performance of electrospun zein nanofibers loaded with eugenol, enhanced through crosslinking with glutaraldehyde vapors. This method shows promise for developing advanced drug delivery systems and food packaging materials (Wang et al., 2024).

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H317,H319
• Precautionary Statements: P261 - P264 - P272 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Sens. 1
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): 255.2 °F - closed cup
• Flash Point(C): 124 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves