Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

A0424

Sigma-Aldrich

Alverine citrate salt

Synonym(s):

N-Ethyl-3,3′-diphenyldipropylamine, NSC 35459

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C20H27N · C6H8O7
CAS Number:
5560-59-8
Molecular Weight:
473.56
EC Number:
226-929-3
MDL number:
MFCD00035086
UNSPSC Code:
12352100
PubChem Substance ID:
57653816
NACRES:
NA.22

form

powder

SMILES string

OC(=O)CC(O)(CC(O)=O)C(O)=O.CCN(CCCc1ccccc1)CCCc2ccccc2

InChI

1S/C20H27N.C6H8O7/c1-2-21(17-9-15-19-11-5-3-6-12-19)18-10-16-20-13-7-4-8-14-20;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-8,11-14H,2,9-10,15-18H2,1H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI key

RYHCACJBKCOBTJ-UHFFFAOYSA-N

Gene Information

human ... HNF4A(3172) , HTR1A(3350)

Looking for similar products? Visit Product Comparison Guide

Application

Used for studies of pharmacological activity including:
  • Synergism with fluconazole against Saccharomyces cerevisiae and Candida albicans
  • Efficacy of combination with simeticone on abdominal pain associated with irritable bowel syndrome
  • Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis
  • Drug effects viewed from a signal transduction network perspective
  • Enhanced cytotoxic effect of proteasome inhibitor MG132
  • Mechanism of action on phasic smooth muscles

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Engin Altintaş et al.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 19(3), 174-179 (2008-12-31)
Successful colonoscopy depends on the insertion of the instrument to the cecum, a detailed examination, and minimal discomfort to the patient during the procedure. The aim of this study was to determine the effects of alverine citrate plus simethicone on
Chinmoy Ghosh et al.
Drug testing and analysis, 2(6), 284-291 (2010-06-22)
A rapid and highly sensitive method for the determination of alverine (ALV) and its metabolite, para hydroxy alverine (PHA), in human plasma using LC-MS/MS in positive ion electrospray ionization (ESI) in multiple reactions monitoring (MRM) mode was developed and validated.
Jee Young Han et al.
The Korean journal of hepatology, 16(1), 75-78 (2010-04-09)
Alverine citrate is one of the most commonly used antispasmodic drugs for patients with irritable bowel syndrome. Alverine-citrate-induced hepatotoxicity is extremely rare, with only a few cases having been reported worldwide. We present a case of a 75-year-old female patient
Alverine citrate, simeticone, and Rome III irritable bowel syndrome.
A C Ford
Alimentary pharmacology & therapeutics, 31(7), 767-768 (2010-04-27)
Samia Ammar et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 16(12), 1156-1161 (2009-05-01)
A sesquiterpenoid Bakkenolide (1), and two steroids, (3beta, 22E)-Stigmasta-5, 22-diène-3-ol (Stigmasterol) (2) and stigmasterol 3beta-glucoside (3), isolated from the Hertia cheirifolia (L.) chloroform extract, were evaluated respectively for their spasmolytic and anti-inflammatory activities. We note that these natural products were
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service