SAB5700485

Anti-Phospho-DPYSL2-T514 antibody produced in rabbit

• Synonym(s): CRMP-2, CRMP2, DHPRP2, DPYSL2, DRP-2, DRP2, N2A3, ULIP-2, ULIP2
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 58; 62
• species reactivity: rat, human, mouse
• concentration: 2.63 mg/ml
• technique(s): western blot: 1:500-1:2000
• UniProt accession no.: Q16555
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pThr514)
• Gene Information: human ... DPYSL2(1808)

Description

General description

This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer′s disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Immunogen

A phospho specific peptide corresponding to residues surrounding T514 of human DPYSL2

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable