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75436

Sigma-Aldrich

L-Ribulose

≥90% (HPLC)

Synonym(s):

L-Adonose, L-erythro-2-Pentulose

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About This Item

Empirical Formula (Hill Notation):
C5H10O5
CAS Number:
Molecular Weight:
150.13
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.28

Assay

≥90% (HPLC)

form

liquid

optical activity

[α]/D +14.5±3.0°, c = 0.1 in H2O

storage temp.

2-8°C

SMILES string

OC[C@H](O)[C@H](O)C(=O)CO

InChI

1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h3,5-8,10H,1-2H2/t3-,5-/m0/s1

InChI key

ZAQJHHRNXZUBTE-UCORVYFPSA-N

Application

L-Ribulose has been used as a substrate in L-arabinose isomerase activity assay and in ribulokinase activity assay.

Biochem/physiol Actions

L-Ribulose is produced from L-ribose by microbial enzymes. L-Ribulose is a rare sugar and a precursor for antiviral drugs synthesis. Major industrial production of L-ribulose is by the use of L-arabinose isomerase enzyme.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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L-Ribulose: a novel chiral pool compound.
Vanhessche, K., et al.
Tetrahedron Letters, 31, 2337-2340 (1990)
Ye-Wang Zhang et al.
Bioprocess and biosystems engineering, 33(6), 741-748 (2009-12-01)
Recombinant Escherichia coli whole cells harboring Bacillus licheniformis L-arabinose isomerase (BLAI) were immobilized with alginate. The operational conditions for immobilization were optimized with response surface methodology. Optimal alginate concentration, Ca(2+) concentration, and cell mass loading were 1.8% (w/v), 0.1 M
Production of L-ribose from L-ribulose by a triple-site variant of mannose-6-phosphate isomerase from Geobacillus thermodenitrificans
Lim YR, et al.
Applied and Environmental Microbiology, AEM-07012 (2012)
Chakkiath Paul Antony et al.
International journal of systematic and evolutionary microbiology, 62(Pt 7), 1613-1618 (2011-09-06)
A moderately haloalkaliphilic methylotrophic bacterium possessing the ribulose monophosphate pathway for carbon assimilation, designated MPL(T), was isolated from Lonar Lake sediment microcosms that were oxidizing methane for two weeks. The isolate utilized methanol and was an aerobic, Gram-negative, asporogenous, motile
Cassandra De Muynck et al.
Journal of chromatography. A, 1101(1-2), 115-121 (2005-10-29)
A new high performance liquid chromatographic (HPLC) method is described for the analysis of ribose, arabinose and ribulose mixtures obtained from (bio)chemical isomerization processes. These processes gain importance since the molecules can be used for the synthesis of antiviral therapeutics.

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