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123M-1

Sigma-Aldrich

CD23 (1B12) Mouse Monoclonal Antibody

clone 1B12, unconjugated, Cell Marque™

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

1B12, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (123M-14)
vial of 0.5 mL concentrate (123M-15)
bottle of 1.0 mL predilute (123M-17)
vial of 1.0 mL concentrate (123M-16)
bottle of 7.0 mL predilute (123M-18)

manufacturer/tradename

Cell Marque™

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:10-1:50

isotype

IgG1κ

control

tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

membranous

Gene Information

human ... FCER2(2208)

Related Categories

General description

This is a B-cell antibody that is useful to differentiate between B-CLL and B-SLL's that are CD23 positive from mantle cell lymphomas and small cleaved lymphomas that are CD23 negative. This antibody reacts with the antigen that is found on a subpopulation of peripheral blood cells, B lymphocytes and on EBV transformed B lymphoblastoid cell lines.

Quality


IVD
IVD
IVD
RUO

Linkage

CD23 Positive Control Slides, Product No. 123S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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F Pezzella et al.
British journal of haematology, 108(2), 369-376 (2000-02-26)
The aim of this study was to establish how effective is the use of immunohistochemistry on formalin-fixed bone marrow in diagnosing low-grade B-cell neoplasms. We investigated a series of 41 consecutive patients with bone marrow involvement for whom no other
G Pallesen
Leucocyte Typing III, 383-386 (1987)
D Kaiserlian et al.
Immunology, 80(1), 90-95 (1993-09-01)
Immunohistochemical analysis of normal human intestine revealed that two anti-CD23 monoclonal antibodies (mAb), EBVCS 1 and EBVCS 2, reacted with human intestinal epithelial cells. Both mAb exhibited an exclusive reactivity with epithelial cells of the small and large bowels. Staining
JP Aubry, et al.
Leucocyte Typing III, 417-419 (1987)
Robert B West et al.
American journal of clinical pathology, 117(4), 636-643 (2002-04-10)
We used a panel of paraffin antibodies to determine whether neoplastic and nonneoplastic lymphoid aggregates in the bone marrow can be distinguished reliably. Formalin-fixed, paraffin-embedded bone marrow core biopsy specimens with lymphoid aggregates were stained using primary antibodies directed against
View All Related Papers

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Antibodies as Raw Material

Trusted IVDR-ready supplier of high-quality Cell Marque™ antibodies for diagnostic pathology and IHC, ensuring reliability and expert support.

Antibodies as Raw Material

Trusted IVDR-ready supplier of high-quality Cell Marque™ antibodies for diagnostic pathology and IHC, ensuring reliability and expert support.

Antibodies as Raw Material

Trusted IVDR-ready supplier of high-quality Cell Marque™ antibodies for diagnostic pathology and IHC, ensuring reliability and expert support.

Antibodies as Raw Material

Trusted IVDR-ready supplier of high-quality Cell Marque™ antibodies for diagnostic pathology and IHC, ensuring reliability and expert support.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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