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Sigma-Aldrich

Bromhexine hydrochloride

≥98.0% (AT)

Synonym(s):

2-Amino-3,5-dibromo-N-cyclohexyl-N-methylbenzylamine hydrochloride, N-(2-Amino-3,5-dibromobenzyl)-N-methylcyclohexylamine hydrochloride, Bromohexine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C14H20Br2N2 · HCl
CAS Number:
611-75-6
Molecular Weight:
412.59
Beilstein:
4848376
EC Number:
210-280-8
MDL number:
MFCD00056626
UNSPSC Code:
12352100
PubChem Substance ID:
329751532
NACRES:
NA.22

Quality Level

100

Assay

≥98.0% (AT)

form

powder

SMILES string

Cl.CN(Cc1cc(Br)cc(Br)c1N)C2CCCCC2

InChI

1S/C14H20Br2N2.ClH/c1-18(12-5-3-2-4-6-12)9-10-7-11(15)8-13(16)14(10)17;/h7-8,12H,2-6,9,17H2,1H3;1H

InChI key

UCDKONUHZNTQPY-UHFFFAOYSA-N

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General description

Bromhexine hydrochloride is a bronchial mucolytic.

Application

Bromhexine hydrochloride was used in the secretion of pancreatic juice of low viscosity.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Tatsuhiro Tsujimoto et al.
Alcoholism, clinical and experimental research, 29(12 Suppl), 272S-276S (2005-12-31)
Abstinence is a prerequisite for the treatment of alcoholic chronic pancreatitis, but there are patients who have repeated attacks because of their inability to abstain and the consequent congestive effects of the continued alcohol intake on pancreatic juice. Bromhexine hydrochloride
Mladen Stojanov et al.
International journal of pharmaceutics, 422(1-2), 349-355 (2011-10-27)
Bromhexine hydrochloride (bromhexine) is a mucolytic agent with very low aqueous solubility. However, with addition of cyclodextrins (CD) to the formulation, this disadvantage may be limited and therapeutic doses of bromhexine in solution can be achieved. The interaction of bromhexine
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