SRP6246

TPO from rat

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

• Synonyme(s) : MGDF, Megakaryocyte colony-stimulating factor, Thrombopoietin, c-MPL Ligand
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.32

Propriétés

• Source biologique: rat
• Produit recombinant: expressed in E. coli
• Pureté: ≥98% (SDS-PAGE)
• Forme: lyophilized powder
• Poids mol.: 18.7 kDa
• Conditionnement: pkg of 10 μg; pkg of 50 μg
• Impuretés: <1 EU/μg endotoxin (LAL test)
• Numéro d'accès UniProt: P49745
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Informations sur le gène: rat ... TPO(81811)

Description

Description générale

TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and murine TPO exhibits cross-species reactivity. Recombinant rat TPO is a fully biologically active 174 amino acid polypeptide (18.7 kDa), which contains the erythropoietin-like domain of the full length TPO protein.

Forme physique

Sterile filtered through a 0.2 micron filter. Lyophilized from Sodium Citrate, pH 4.5.

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable