SRP6099

GSTM1 from mouse

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

• Synonyme(s) : GST 1-1, GST class-mu1, Glutathione S-transferase Mu 1, pmGT10
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.32

Propriétés

• Source biologique: mouse
• Produit recombinant: expressed in E. coli
• Essai: ≥95% (SDS-PAGE)
• Forme: liquid
• Poids mol.: 25.9 kDa
• Conditionnement: pkg of 100 μg
• Numéro d'accès NCBI: P10649
• Numéro d'accès UniProt: P10649
• Conditions d'expédition: dry ice
• Température de stockage: −70°C
• Informations sur le gène: mouse ... GSTM1(14862)

Description

Description générale

GSTM1 (glutathione S-transferase μ 1) belongs to the superfamily of glutathione-S-transferases. It belongs to the μ class of soluble GSTs. GSTM1 is strongly expressed in the kidneys.[1]

Actions biochimiques/physiologiques

Members of GST (glutathione S-transferase) superfamily are responsible for the metabolism of various reactive oxygen species and xenobiotics. GSTM1 (GST μ 1) plays a significant role in vascular homeostasis. Humans with null allele, GSTM1(0), are at increased risks for colon and lung cancers, hypertension, and atherosclerosis, and have higher DNA changes in atherosclerotic lesions of the abdominal aorta.[1]

Forme physique

1 mg/mL solution in PBS (pH 7.4) containing 5 mM Glutathione

Notes préparatoires

Centrifuge the vial prior to opening.

Autres remarques

MPMILGYWNV RGLTHPIRML LEYTDSSYDE KRYTMGDAPD FDRSQWLNEK FKLGLDFPNL PYLIDGSHKI TQSNAILRYL ARKHHLDGET EEERIRADIV ENQVMDTRMQ LIMLCYNPDF EKQKPEFLKT IPEKMKLYSE FLGKRPWFAG DKVTYVDFLA YDILDQYRMF EPKCLDAFPN LRDFLARFEG LKKISAYMKS SRYIATPIFS KMAHWSNK

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable