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SRP3054

Sigma-Aldrich

HCC-1 Peptide

≥98% (HPLC), human recombinant, expressed in E. coli, suitable for cell culture, 72 aa

Synonyme(s) :

CCL14, HCC-1/HCC-3, Hemofiltrate CC Chemokine-1, NCC-2

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About This Item

Code UNSPSC :
12352202
Nomenclature NACRES :
NA.32

product name

HCC-1 (CCL14) (72 aa) human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

Source biologique

human

Produit recombinant

expressed in E. coli

Pureté

≥98% (HPLC)
≥98% (SDS-PAGE)

Forme

lyophilized

Puissance

5.0-20.0 ng/mL

Poids mol.

7.9 kDa

Conditionnement

pkg of 10 μg

Technique(s)

cell culture | mammalian: suitable

Impuretés

<0.1 EU/μg endotoxin, tested

Couleur

white to off-white

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Température de stockage

−20°C

Informations sur le gène

human ... CCL14(6358)

Description générale

HCC-1 is a CC chemokine that signals through the CCR1 receptor and chemoattracts blood monocytes. It is secreted by various tissues including skeletal muscle, heart, spleen, liver and bone marrow. Recombinant human HCC-1 is an 8.4 kDa protein consisting of 72 amino acids including the four highly conserved residues present in CC chemokines.

Actions biochimiques/physiologiques

HCC-1 is a CC chemokine that signals through the CCR1 receptor and chemoattracts blood monocytes. Recombinant human HCC-1 is an 8.4 kDa protein consisting of 72 amino acids including the four highly conserved residues present in CC chemokines.

Séquence

TESSSRGPYH PSECCFTYTT YKIPRQRIMD YYETNSQCSK PGIVFITKRG HSVCTNPSDK WVQDYIKDMK EN

Forme physique

Lyophilized with no additives.

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

C L Tsou et al.
The Journal of experimental medicine, 188(3), 603-608 (1998-08-04)
Hemofiltrate C-C chemokine (HCC)-1 is a recently cloned C-C chemokine that is structurally similar to macrophage inflammatory protein (MIP)-1alpha. Unlike most chemokines, it is constitutively secreted by tissues and is present at high concentrations in normal human plasma. Also atypical
P Schulz-Knappe et al.
The Journal of experimental medicine, 183(1), 295-299 (1996-01-01)
A novel CC chemokine, HCC-1, was isolated from the hemofiltrate of patients with chronic renal failure. HCC-1 has a relative molecular mass of 8,673 and consists of 74 amino acids including four cysteines linked to disulfide bonds. HCC-1 cDNA was

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