SML0342

TFM-4AS-1

≥98% (HPLC)

• Synonyme(s) : (4aR,6aS,7S,11aR)-1,4a,6a-Trimethyl-2-oxo-N-[2-(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11atetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide
• Formule empirique (notation de Hill): C₂₇H₃₃F₃N₂O₂
• Numéro CAS: 188589-61-9
• Poids moléculaire : 474.56
• Code UNSPSC : 51111800
• ID de substance PubChem : 329825347
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Pureté: ≥98% (HPLC)
• Forme: powder
• Couleur: white to beige
• Solubilité: DMSO: >5 mg/mL
• Température de stockage: 2-8°C
• Chaîne SMILES: CN1[C@@H]2CC[C@@H]3[C@@H]4CC[C@H](C(=O)Nc5ccccc5C(F)(F)F)[C@@]4(C)CC[C@@H]3[C@@]2(C)C=CC1=O
• InChI: 1S/C27H33F3N2O2/c1-25-14-12-18-16(8-11-22-26(18,2)15-13-23(33)32(22)3)17(25)9-10-20(25)24(34)31-21-7-5-4-6-19(21)27(28,29)30/h4-7,13,15-18,20,22H,8-12,14H2,1-3H3,(H,31,34)/t16-,17+,18+,20-,22-,25+,26-/m1/s1
• Clé InChI: YFBLEKKYWFJKBP-HNXMFXTHSA-N

Description

Actions biochimiques/physiologiques

TFM-4AS-1 is a potent SARM (Selective Androgen Receptor Modulator). TFM-4AS-1 is a partial agonist of AR. The compound promotes the buildup of bone and muscle mass while having reduced effects on reproductive organs and sebaceous glands. The compound also is an inhibitor of rat 5 α-reductase enzymes type I (2 nM) and type 2 (3 nM).

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable