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SIRNA

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Custom and Predesigned siRNA

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Custom siRNA, High-throughput siRNA, Predesigned siRNA, siRNA, siRNA pools

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MISSION® esiRNA targeting human SEMA3B

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MISSION® esiRNA

Fuhui Xu et al.
PloS one, 9(9), e106509-e106509 (2014-09-04)
Improved drought tolerance is always a highly desired trait for agricultural plants. Significantly increased drought tolerance in Arabidopsis thaliana (Columbia-0) has been achieved in our work through the suppression of ESKMO1 (ESK1) gene expression with small-interfering RNA (siRNA) and overexpression
Antonis C Antoniou et al.
The New England journal of medicine, 371(6), 497-506 (2014-08-08)
Germline loss-of-function mutations in PALB2 are known to confer a predisposition to breast cancer. However, the lifetime risk of breast cancer that is conferred by such mutations remains unknown. We analyzed the risk of breast cancer among 362 members of
Maria Dermit et al.
Developmental cell, 55(3), 298-313 (2020-11-11)
Translation of ribosomal protein-coding mRNAs (RP-mRNAs) constitutes a key step in ribosome biogenesis, but the mechanisms that modulate RP-mRNA translation in coordination with other cellular processes are poorly defined. Here, we show that subcellular localization of RP-mRNAs acts as a
Chong He et al.
PLoS genetics, 10(12), e1004860-e1004860 (2014-12-19)
The common non-steroidal anti-inflammatory drug ibuprofen has been associated with a reduced risk of some age-related pathologies. However, a general pro-longevity role for ibuprofen and its mechanistic basis remains unclear. Here we show that ibuprofen increased the lifespan of Saccharomyces
Yanli Ma et al.
PloS one, 7(10), e47961-e47961 (2012-11-01)
Aflatoxin B1 (AFB1) is a potent carcinogen that can induce hepatocellular carcinoma. AFB1-8,9-exo-epoxide, one of AFB1 metabolites, acts as a mutagen to react with DNA and induce gene mutations, including the tumor suppressor p53. In addition, AFB1 reportedly stimulates IGF
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Long Oligos

Techniques for long oligo synthesis and purification offer superior quality unmatched by other suppliers.

Oligos cGMP personnalisés

Si vous commercialisez des produits de diagnostic moléculaire (MDx), mettez au point des tests développés en laboratoire (LDT) ou menez des recherches précliniques sur des produits thérapeutiques, votre kit, test ou modalité final(e) doit présenter un niveau de qualité extraordinaire pour répondre à des normes réglementaires ou d'étude strictes.

Molecular Beacons

Learn about precision Sigma-Aldrich Molecular Beacon oligonucleotide probes used for sequence detection in qPCR for in vitro research.

Positive Control siRNA

MISSION Positive Control siRNA, validated for siRNA silencing experiments, saves time in gene silencing research.

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Custom siRNA Duplex Plates

Use our synthetic, small interfering RNA (siRNA) duplex plates to identify gene function, elucidate pathways, and screen for potential new drug targets.

Fast siRNA

We can quickly synthesize and ship custom siRNA using your sequences.

Easy Oligo

Easy Oligo is suitable for a wide range of applications including PCR , sequencing and real-time quantitative PCR (as a primer)

Oligos cGMP personnalisés

Si vous commercialisez des produits de diagnostic moléculaire (MDx), mettez au point des tests développés en laboratoire (LDT) ou menez des recherches précliniques sur des produits thérapeutiques, votre kit, test ou modalité final(e) doit présenter un niveau de qualité extraordinaire pour répondre à des normes réglementaires ou d'étude strictes.

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