SAB5702848

Anti-eIF5A Antibody, clone 3R10I7, Rabbit Monoclonal

• Synonyme(s) : EIF-5A, EIF5A1, eIF5AI
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.46

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Matériaux: colorless
• Clone: 3R10I7, monoclonal
• Forme: liquid
• Poids mol.: 18 kDa
• Espèces réactives: rat, human, rat
• Concentration: 0.09 mg/mL
• Technique(s): western blot: 1:500 - 1:2000
• Couleur: colorless

Description

Description générale

mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1 Rex protein and of human immunodeficiency virus type 1 (HIV-1 Rev protein, essential for mRNA export of retroviral transcripts.

Immunogène

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human eIF5A (P63241).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1