SAB5500153

Anti-N-RAS antibody, Rabbit monoclonal

clone SP174, recombinant, expressed in proprietary host, affinity isolated antibody

• Synonyme(s) : Anti-ALPS4, Anti-CMNS, Anti-KRAS, Anti-N-ras, Anti-NCMS, Anti-NRAS1, Anti-NS6
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Produit recombinant: expressed in proprietary host
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: SP174, monoclonal
• Espèces réactives: human (tested)
• Technique(s): immunoblotting: 1:400; immunohistochemistry: 1:100
• Isotype: IgG
• Numéro d'accès UniProt: P01111
• Conditions d'expédition: wet ice
• Température de stockage: 2-8°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... NRAS(4893)

Description

Description générale

GTPase N-Ras or N-Ras is a guanine-nucleotide binding protein. Receptor tyrosine kinases and G-protein-coupled receptors activate Ras, which then stimulates the MAPK signal pathway. Point mutations (Q61R) in Ras prevent the GAP-mediated inhibition of the MAPK pathway in certain cancers such as lung carcinoma and melanoma. Abnormal MAPK signaling may lead to uncontrolled cell proliferation, resistance to both apoptosis and cancer therapy.

Immunogène

Synthetic peptide of human N-Ras protein containing N-Ras (Q61R) point mutation.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable