SAB4702019

Monoclonal Anti-CD82 purified low endotoxin produced in mouse

• Synonyme(s) : 4F9, C33, GR15, IA4, KAI1, R2, SAR2, ST6, TSPAN27
• Code UNSPSC : 12352203

Propriétés

• Conjugué: unconjugated
• Niveau de qualité: 100
• Type de produit anticorps: primary antibodies
• Clone: C33, monoclonal
• Forme: buffered aqueous solution
• Espèces réactives: human
• Concentration: 1 mg/ml
• Technique(s): FUNC: suitable; flow cytometry: suitable; immunocytochemistry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• Isotype: IgG2a
• Numéro d'accès UniProt: P27701
• Température de stockage: 2-8°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... CD82(3732)

Description

Description générale

CD82 (KAI1), a member of the tetraspanin family, forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules. These complexes influence adhesion, morphology, activation, proliferation and differentiation of B, T and other cells. CD82 regulates cytoskeleton rearrangement and may participate in the turnover of the tetraspanin complex members. Besides in the plasma membrane, CD82 is localized also in endosome/lysosome compartments. Tumour-suppressive roles of CD82 have been demonstrated.

Spécificité

The mouse monoclonal antibody C33 recognizes an extracellular/luminal epitope of CD82, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.

Immunogène

C91/PL (human HTLV-1+ T cell line)

Forme physique

Phosphate buffered saline (PBS), pH 7.4

Notes préparatoires

Purified by protein-A affinity chromatography.

Stockage et stabilité

Store at 2-8°C. Do not freeze.

Autres remarques

The antibody solution should be gently mixed before use.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1