SAB4502884

Anti-ELOVL4 antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : Elongation of very long chain fatty acids protein 4
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41
• Conjugué: unconjugated
• application: ELISA; WB
• Clone: polyclonal
• Espèces réactives: mouse, human
• citations: 3
• Technique(s): ELISA: 1:40000; western blot: 1:500-1:1000

Propriétés

• Source biologique: rabbit
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 36 kDa
• Espèces réactives: mouse, human
• Concentration: ~1 mg/mL
• Technique(s): ELISA: 1:40000; western blot: 1:500-1:1000
• Numéro d'accès NCBI: Q9GZR5
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... ELOV4(6785)

Description

Description générale

Anti-ELOVL4 antibody detects endogenous levels of total ELOVL4 protein.

The ELOVL4 (elongation of very long chain fatty acids protein 4) gene is mapped to human chromosome 6q14.1. The encoded protein localizes to endoplasmic reticulum. ELOVL4 protein consists of five transmembrane domains, a histidine cluster motif and di-lysine motif at the C-terminus.

Immunogène

The antiserum was produced against synthesized peptide derived from human ELOVL4.

Immunogen Range: 41-90

Actions biochimiques/physiologiques

ELOVL4 (elongation of very long chain fatty acids protein 4) plays an important role in the biosynthesis of very long chain fatty acids (both saturated and unsaturated) in the retina, meibomian gland, skin, testis and brain. Mutation in the gene causes autosomal dominant Stargardt3 macular dystrophy. Variation in ELOVL4 results in spastic quadriplegia, ichthyosis and intellectual disability leading to neuro-ichthyotic disorder.

Caractéristiques et avantages

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Forme physique

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable