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SAB4300426

Sigma-Aldrich

Anti-NOS1 (Ab-852) antibody produced in rabbit

affinity isolated antibody

Synonyme(s) :

Anti-IHPS1 antibody produced in rabbit, Anti-NOS antibody produced in rabbit, Anti-nNOS antibody produced in rabbit, Anti-nitric oxide synthase 1 (neuronal) antibody produced in rabbit

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About This Item

Numéro MDL:
MFCD01092550
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Poids mol.

~160 kDa

Espèces réactives

mouse, rat, human

Concentration

1 mg/mL

Technique(s)

indirect immunofluorescence: 1:100-1:200

Isotype

IgG

Séquence immunogène

(F-N-S-V-S)

Numéro d'accès NCBI

NP_000611.1

Numéro d'accès UniProt

P29475

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... NOS1(4842)

Catégories apparentées

Description générale

NOS1 (nitric oxide synthase 1) is one of the NOS (nitric oxide synthase) isoforms found in the heart. It is located on human chromosome 12q24.2-31. It is mainly localized in the sarcoplasmic reticulum (SR).

Immunogène

Peptide sequence around aa. 850-854 (F-N-S-V-S), according to the protein NOS1.

Application

Anti-NOS1 (Ab-852) antibody has been used in immunocytochemistry .

Actions biochimiques/physiologiques

NOS (nitric oxide synthase) produce nitric oxide in the heart.It regulates myocardial function and plays an important role in the remodeling of human (ICM) ischemic cardiomyopathy.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Description de la cible

Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter.

Forme physique

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Ana C Bahia et al.
PLoS neglected tropical diseases, 5(11), e1317-e1317 (2011-11-10)
Malaria affects 300 million people worldwide every year and 450,000 in Brazil. In coastal areas of Brazil, the main malaria vector is Anopheles aquasalis, and Plasmodium vivax is responsible for the majority of malaria cases in the Americas. Insects possess
Converging evidence for an impact of a functional NOS gene variation on anxiety-related processes
Kuhn M, et al.
Social Cognitive and Affective Neuroscience, 11(5), 803-812 (2016)
The JAK-STAT pathway controls Plasmodium vivax load in early stages of Anopheles aquasalis infection
Bahia AC, et al.
PLoS Neglected Tropical Diseases, 5(11) (2011)
Roles of nitric oxide and superoxide in inflammation.
Daniela Salvemini et al.
Methods in molecular biology (Clifton, N.J.), 225, 291-303 (2003-05-29)

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