SAB2500067

Anti-Amphiphysin/AMPH antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• Synonyme(s) : Anti-AMPH1, Anti-HGNC:471
• Numéro MDL: MFCD01633026
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: goat
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Espèces réactives: human, rat, canine, mouse
• Technique(s): immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• Numéro d'accès UniProt: P49418
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... AMPH(273)

Description

Description générale

AMPH (Amphiphysin) is a 128kD peripheral protein highly distributed in nervous system including many neurons, certain endocrine cell types, and spermatocytes. It exists as two isoforms having different molecular weights 128 and 108kD respectively, in breast cancer. In human, it is located on chromosome 7, region p13-p14. It is a member of amphiphysin family and consists of an SH3 domain.

Immunogène

Peptide with sequence C-KRKDESRISKAE from the internal region of the protein sequence according to NP_001626.1; NP_647477.1.

Application

Anti-Amphiphysin/AMPH antibody produced in goat is suitable for western blot.

Actions biochimiques/physiologiques

AMPH (Amphiphysin) is involved in several pleotropic functions including endocytosis, actin function, and cell growth control. It plays an important role in synaptic vesicle endocytosis of axon terminals. Alteration in AMPH gene is associated with heritable disorders of the nervous system, endocrine tissues and male fertility. It also has correlation with a rare neurologic autoimmune disease, paraneoplastic Stiff-Man syndrome. It is also involved in the neoplastic growth cone dynamics.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319
• Conseils de prudence: P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2
• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable