S7029
[Pro9]-Substance P
≥97% (HPLC)
Synonyme(s) :
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Pro-Leu-Met-NH2
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About This Item
Formule empirique (notation de Hill):
C66H102N18O13S
Numéro CAS:
Poids moléculaire :
1387.69
Numéro MDL:
Code UNSPSC :
12352200
ID de substance PubChem :
Essai
≥97% (HPLC)
Température de stockage
−20°C
Chaîne SMILES
CSCCC(NC(=O)C(CC(C)C)NC(=O)C1CCCN1C(=O)C(Cc2ccccc2)NC(=O)C(Cc3ccccc3)NC(=O)C(CCC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C4CCCN4C(=O)C(CCCCN)NC(=O)C5CCCN5C(=O)C(N)CCCNC(N)=N)C(N)=O
Code de la classe de stockage
13 - Non Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
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Y Torrens et al.
Peptides, 16(4), 587-594 (1995-01-01)
The selective NK2 agonist [Lys5-MeLeu9,Nle10]NKA(4-10) markedly stimulated [3H]inositol monophosphate (PI1) formation in prisms from the rat urinary bladder. This response was blocked by the NK2 antagonist SR 48968. Senktide (NK3 agonist) was inactive. Septide, a short SP analogue, and the
Y Torrens et al.
Journal of neurochemistry, 70(5), 2091-2098 (1998-05-08)
In [3H]myristic acid-prelabeled Chinese hamster ovary cells stably expressing the rat NK1 tachykinin receptor, the selective NK1 agonist [Pro9]substance P ([Pro9]SP) time and concentration dependently stimulated the formation of [3H]phosphatidylethanol in the presence of ethanol. This [Pro9]SP-induced activation of phospholipase
C Gauchy et al.
Neuroscience, 73(4), 929-939 (1996-08-01)
The effects of septide (a short substance P C-terminal analogue) and of the neurokinin-1 receptor agonist [Pro9]substance P on the N-methyl-D-aspartate (50 microM)-evoked release of [3H]dopamine (continuously synthesized from [3H]tyrosine) were investigated in the absence or the presence of the
S Lavielle et al.
European journal of pharmacology, 258(3), 273-276 (1994-06-13)
In the guinea-pig ileum tissue, [Pro9]substance P, a tachykinin NK1 receptor selective agonist and septide, [pGlu6,Pro9]-substance P-(6-11), do not interact with the same receptor as shown by the different inhibitory profiles of GR 72251 and [D-Pro9,Pro10,Trp11]substance P. Substitution at position
J C Delumeau et al.
Journal of neurochemistry, 57(6), 2026-2035 (1991-12-01)
The effects on cytosolic Ca2+ concentration of 2-chloroadenosine and [L-Pro9]-substance P, a selective agonist of NK1 receptors, were investigated on astrocytes from embryonic mice in primary culture. Cells responded to [L-Pro9]-substance P with a transitory increase in cytosolic Ca2+ which
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